Results 61 to 70 of about 5,136 (200)

Determinants of Intradialytic Phosphate Removal in Hemodiafiltration From Real‐World Clinical Practice

open access: yesArtificial Organs, EarlyView.
We show that convective therapy in the form of hemodiafiltration does not demonstrate a measurable effect on phosphate removal in a real‐world setting. On the other hand, session duration is the most important factor in determining phosphate removal in hemodialysis patients.
David A. Jaques   +4 more
wiley   +1 more source

Proteomic profiling of senescent human diploid fibroblasts treated with gamma-tocotrienol

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Replicative senescence of human diploid fibroblasts (HDFs) has been used as a model to study mechanisms of cellular aging. Gamma-tocotrienol (γT3) is one of the members of vitamin E family which has been shown to increase proliferation of ...
Jen-Kit Tan   +2 more
doaj   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Targeting Mitochondria in Melanoma

open access: yesBiomolecules, 2020
Drastically elevated glycolytic activity is a prominent metabolic feature of cancer cells. Until recently it was thought that tumor cells shift their entire energy production from oxidative phosphorylation (OXPHOS) to glycolysis.
Sepideh Aminzadeh-Gohari   +5 more
doaj   +1 more source

MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing

open access: yesScientific Reports, 2017
MicroRNA (miR)-132 has been identified as a top up-regulated miRNA during skin wound healing and its inhibition impairs wound repair. In a human in vivo surgical wound model, we showed that miR-132 was induced in epidermal as well as in dermal wound–edge
Xi Li   +6 more
doaj   +1 more source

Stress-stimulated epinephrine induces premature senescence in dermal fibroblasts and contributes to impaired skin wound healing [PDF]

open access: yesBrazilian Journal of Medical and Biological Research
External factors accelerate cellular senescence in the skin and compromise its repair process. Psychological stress impairs skin wound healing, but no study examined its role in cellular senescence during skin tissue repair.
J.T. da Silva   +4 more
doaj   +1 more source

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

open access: yesAdvanced Functional Materials, Volume 36, Issue 22, 16 March 2026.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr   +9 more
wiley   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández   +4 more
wiley   +1 more source

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song   +17 more
wiley   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim   +11 more
wiley   +1 more source

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