Results 151 to 160 of about 1,867,283 (205)

HDL and atherosclerosis: Insights from inherited HDL disorders

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015
Plasma high density lipoproteins (HDL) comprise a highly heterogeneous family of lipoprotein particles, differing in density, size, surface charge, and lipid and protein composition. Epidemiological studies have shown that plasma HDL level inversely correlates with atherosclerotic cardiovascular disease.
L. Calabresi   +4 more
openaire   +4 more sources

HDL concentration, lipid transfer to HDL, and HDL size in normolipidemic nonobese menopausal women

open access: yesInternational Journal of Gynecology & Obstetrics, 2008
AbstractObjectiveTo determine the impact of menopause on lipid transfer from donor lipoproteins to high‐density lipoproteins (HDLs)—a process that is related to the protective function of HDL—and the size of HDL particles.MethodPlasma from 22 premenopausal and 18 postmenopausal nonobese, normolipidemic women paired for age (40–50 years) was incubated ...
Arícia H, Giribela   +4 more
openaire   +3 more sources

HDL genes & HDL drugs

open access: yes, 2011
Menno Vergeer onderzocht de genetische basis van het menselijk HDL-cholesterolmetabolisme door middel van familieonderzoek en genetische associatiestudies in grote cohorten. Mutaties in verschillende cholesterolvervoerders zijn van invloed op de productie van insuline in de alvleesklier en van steroïdhormonen in de bijnier. Daarnaast blijken genetische
Vergeer, A.M.H.
openaire   +2 more sources

HDL in the 21st Century: A Multifunctional Roadmap for Future HDL Research [PDF]

open access: yesCirculation, 2021
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular risk.
Anand Rohatgi   +2 more
exaly   +2 more sources

HDL Structure

2022
HDL has various protein components, including enzymes, complement components, apolipoproteins, protease inhibitors, etc. In addition to proteins, lipids are also a significant component of HDL. These components and their structure determine the function of HDL. HDL is heavily involved in the acute response phase, complement regulation phase, hemostasis
Siying, Deng, Yangkai, Xu, Lemin, Zheng
openaire   +2 more sources

HDL and Sepsis

2022
Sepsis has been recognized as a global health burden in the year 2017 for its high morbidity and mortality. HDL, a cholesterol transporter, also plays vital role in inflammation besides its typical role in reverse cholesterol transportation. In septic patients, HDL levels dropped significantly.
Huanhuan, Cao, Wei, Huang
openaire   +2 more sources

HDL and Diabetes

2022
Diabetes is a worldwide public health issue, with the number of cases expected to reach 642 million by 2040. Patients with diabetes are at a two- to four-fold increased risk of developing cardiovascular disease. This chapter focuses on the anti-diabetic and cardioprotective functions of plasma high-density lipoproteins (HDLs).
Blake J, Cochran   +2 more
openaire   +2 more sources

HDL and Therapy

2022
A wealth of evidence indicates that high-density lipoprotein assumes the unique antiatherosclerosis and other cardioprotective properties. Based on that, HDL-C has been considered as a promising therapy target to reduce the cardiovascular diseases.
Ke, Li, Xianwei, Xie, Yansong, Guo
openaire   +2 more sources

HDL and microRNAs

2022
In previous chapters, we know that high-density lipoproteins (HDLs) could act at multiple cell lines and then trigger intracellular molecular pathway to prevent several metabolic diseases. Besides the classic genes regulating cholesterol efflux and reverse cholesterol transport (RCT), microRNAs (miRNAs) could also affect HDLs biogenesis, metabolism ...
Hongtu, Cui, Kaixuan, Lv, Nana, Yang
openaire   +2 more sources

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