Results 131 to 140 of about 2,675,526 (303)

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

open access: yesBMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang   +8 more
wiley   +1 more source

Five‐Year Clinical Outcomes of Biodegradable Versus Durable Polymer Drug‐Eluting Stents: A Propensity Score‐Matched Analysis of 4394 Patients

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Biodegradable‐polymer (BP) drug‐eluting stents (DES) were developed to mitigate potential late adverse events related to persistent durable polymers in durable‐polymer (DP) DES; however, contemporary long‐term real‐world comparative data remain limited. Aims We aimed to compare the 5‐year clinical outcomes of contemporary BP‐DES and
Yangyoun Lee   +6 more
wiley   +1 more source

The Effect of the MTHFR C677T Genotype Polymorphism on the Efficacy of Folic Acid Treatment for Hyperhomocysteinemia and Cardiovascular Endothelial Function

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Flowchart of patient enrollment. ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with hyperhomocysteinemia (HHcy).
Xiaohui Dou   +8 more
wiley   +1 more source

Short‐Term Effects of Golden Rice Cookies Enriched With Piper crocatum Extract on Lipid Profiles in Adults With Diabetes: A Quasi‐Experimental Study

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) commonly coexists with dyslipidemia and elevated cardiovascular risk. Food‐based interventions containing antioxidants and polyphenols may support lipid metabolism. This study evaluated the short‐term effects of Golden Rice cookies enriched with active Piper crocatum extract on lipid profiles in adults with DM.
Altje Suwardi Abram   +2 more
wiley   +1 more source

Relationship of Serum Levels of High Density Lipoprotein (HDL) and Low Density Lipoprotein (LDL) with the Severity of Parkinson\'s Disease in an Animal Model [PDF]

open access: yesIranian South Medical Journal
Background: Parkinson's disease (PD) is the second most common neurodegenerative disease. Oxidative stress and dyslipidemia may play a key role in the pathogenesis and progression of PD.
Hashem Haghdoost Yazdi   +3 more
doaj  

Primary genetic disorders affecting high density lipoprotein (HDL)

open access: yes, 2018
There is extensive evidence demonstrating that there is a clear inverse correlation between plasma high density lipoprotein cholesterol (HDL-C) concentration and cardiovascular disease (CVD).
Constantine E Kosmas   +5 more
core   +1 more source

Triglyceride Polygenic Score Identifies Individuals Who May Respond Differently to Aspirin in Primary Prevention

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Low‐dose aspirin is no longer routinely recommended for the primary prevention of cardiovascular disease in older adults due to a lack of net benefit over bleeding risk. We hypothesized that genetic subgroups may experience differential harm or benefit from aspirin therapy.
Peter D. Fransquet   +8 more
wiley   +1 more source

Impact of Drone Versus Car Transport on Anti‐Doping Sample Integrity Over Short Distances: A Proof‐Of‐Concept Study

open access: yesDrug Testing and Analysis, EarlyView.
This proof‐of‐concept study evaluated the impact of short‐distance drone transport on anti‐doping sample integrity compared with traditional car transport. Targeted assays and untargeted metabolomics revealed equivalent biological profiles between methods, confirming that drone delivery preserves sample integrity for the athlete biological passport ...
I. Al‐Mohannadi   +13 more
wiley   +1 more source

A NOVEL ROLE FOR HDL AND D-HDL IN PULMONARY IMMUNITY

open access: yes, 2018
Cardiovascular and pulmonary diseases are leading causes of morbidity and mortality worldwide. Studies report an inverse correlation between levels of serum high-density lipoprotein (HDL) and the severity of cardiovascular and lung diseases. HDL has also
Yaeger, Michael
core   +1 more source

Plasma levels of non-HDL cholesterol and HDL cholesterol.

open access: yes, 2013
Plasma was collected from PLTPwt/wt→LDLR−/−, huPLTPtg/wt→LDLR−/−, and huPLTPtg/tg→LDLR−/− recipient mice at the end of the high fat, high cholesterol diet period (i.e., at time of sacrifice) and separated into two fractions: d1.063 g/L (HDL) by ...
Frank Grosveld (63633)   +7 more
core   +1 more source

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