Results 11 to 20 of about 159,686 (49)
Drugs in Context, 2018 Several prospective epidemiological studies have shown that there is a clear inverse relationship between serum high-density lipoprotein-cholesterol (HDL-C) concentrations and risk for coronary heart disease (CHD), even at low-density lipoprotein ...
C. E. Kosmas +7 more
semanticscholar +1 more source
Biological Consequences of Dysfunctional HDL.
Current Medicinal Chemistry, 2019 Epidemiological studies have suggested an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and the risk of cardiovascular disease. HDLs promote reverse cholesterol transport (RCT) and possess several putative atheroprotective
A. Pirillo, A. Catapano, G. Norata
semanticscholar +1 more source
Diabetes Care, 2017 OBJECTIVE High triglyceride (TG) levels and low HDL cholesterol (HDL-C) levels are risk factors for cardiovascular disease. It is unclear whether this relationship depends on glycemic dysregulation, sex, or LDL cholesterol (LDL-C) level.
Jennifer S. Lee +5 more
semanticscholar +1 more source
HDL cholesterol: reappraisal of its clinical relevance
Clinical Research in Cardiology, 2017 BackgroundWhile several lines of evidence prove that elevated concentrations of low-density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its clinical consequences, high-density lipoproteins are still widely believed to
W. März +9 more
semanticscholar +1 more source
HDL from an Alzheimer's disease perspective
Current Opinion in Lipidology, 2019 Purpose of review We review current knowledge regarding HDL and Alzheimer's disease, focusing on HDL's vasoprotective functions and potential as a biomarker and therapeutic target for the vascular contributions of Alzheimer's disease.
Emily B Button +5 more
semanticscholar +1 more source
Effects of Dietary Flavonoids on Reverse Cholesterol Transport, HDL Metabolism, and HDL Function.
Advances in Nutrition, 2017 Strong experimental evidence confirms that HDL directly alleviates atherosclerosis. HDL particles display diverse atheroprotective functions in reverse cholesterol transport (RCT), antioxidant, anti-inflammatory, and antiapoptotic processes.
Courtney L Millar +2 more
semanticscholar +1 more source
The role and function of HDL in patients with diabetes mellitus and the related cardiovascular risk
Lipids in Health and Disease, 2017 Diabetes mellitus (DM) is a major public health problem which prevalence is constantly raising, particularly in low- and middle-income countries.
Marek Femlak +3 more
semanticscholar +1 more source
HDL in CKD-The Devil Is in the Detail.
Journal of the American Society of Nephrology, 2018 The picture of HDL cholesterol (HDL-C) as the "good" cholesterol has eroded. This is even more surprising because there exists strong evidence that HDL-C is associated with cardiovascular disease (CVD) in the general population as well as in patients ...
F. Kronenberg
semanticscholar +1 more source
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
Nature Communications, 2017 Brown and beige adipocytes combust nutrients for thermogenesis and through their metabolic activity decrease pro-atherogenic remnant lipoproteins in hyperlipidemic mice. However, whether the activation of thermogenic adipocytes affects the metabolism and
A. Bartelt +21 more
semanticscholar +1 more source
Circulation Research, 2015 RATIONALE High-density lipoprotein (HDL) is a heterogeneous population of particles. Differences in the capacities of HDL subfractions to remove cellular cholesterol may explain variable correlations between HDL-cholesterol and cardiovascular risk and ...
S. Wales +18 more
semanticscholar +1 more source