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2022
HDL has various protein components, including enzymes, complement components, apolipoproteins, protease inhibitors, etc. In addition to proteins, lipids are also a significant component of HDL. These components and their structure determine the function of HDL. HDL is heavily involved in the acute response phase, complement regulation phase, hemostasis
Siying, Deng, Yangkai, Xu, Lemin, Zheng
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HDL has various protein components, including enzymes, complement components, apolipoproteins, protease inhibitors, etc. In addition to proteins, lipids are also a significant component of HDL. These components and their structure determine the function of HDL. HDL is heavily involved in the acute response phase, complement regulation phase, hemostasis
Siying, Deng, Yangkai, Xu, Lemin, Zheng
openaire +2 more sources
Current Opinion in Lipidology, 2012
HDL cholesterol concentration is inversely correlated with cardiovascular disease and has a wide range of functions involved in many systems. The purpose of this review is to summarize HDL functionality, its relevance to atherosclerosis and factors affecting HDL functions.The contribution of HDL to reverse cholesterol transport may not be as great as ...
Handrean, Soran +3 more
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HDL cholesterol concentration is inversely correlated with cardiovascular disease and has a wide range of functions involved in many systems. The purpose of this review is to summarize HDL functionality, its relevance to atherosclerosis and factors affecting HDL functions.The contribution of HDL to reverse cholesterol transport may not be as great as ...
Handrean, Soran +3 more
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HDL Subfractions, HDL Receptors and HDL Turnover
1987Plasma lipoproteins can be classified according to density, size or electrophoretic mobility. The latter is based on the apolipoprotein composition. Alaupovic1 proposed a distinction between so-called simple lipoproteins, containing only one apolipoprotein, and complex lipoproteins, containing more than one apolipoprotein. Recent publications show that
van Tol, A. +3 more
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2022
Since therapeutic strategies designed to raise HDL failed to exert the expected effective cardiovascular disease (CVD) outcomes in clinical trials, how to improve HDL function rather than its plasma level has become a new focus of scientists' attention. Numerous HDL mimetic peptides have been designed and investigated in various animal models in recent
Jie, Chen, Jiewen, Liu, Baoqi, Yu
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Since therapeutic strategies designed to raise HDL failed to exert the expected effective cardiovascular disease (CVD) outcomes in clinical trials, how to improve HDL function rather than its plasma level has become a new focus of scientists' attention. Numerous HDL mimetic peptides have been designed and investigated in various animal models in recent
Jie, Chen, Jiewen, Liu, Baoqi, Yu
openaire +2 more sources
2022
Sepsis has been recognized as a global health burden in the year 2017 for its high morbidity and mortality. HDL, a cholesterol transporter, also plays vital role in inflammation besides its typical role in reverse cholesterol transportation. In septic patients, HDL levels dropped significantly.
Huanhuan, Cao, Wei, Huang
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Sepsis has been recognized as a global health burden in the year 2017 for its high morbidity and mortality. HDL, a cholesterol transporter, also plays vital role in inflammation besides its typical role in reverse cholesterol transportation. In septic patients, HDL levels dropped significantly.
Huanhuan, Cao, Wei, Huang
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2022
Diabetes is a worldwide public health issue, with the number of cases expected to reach 642 million by 2040. Patients with diabetes are at a two- to four-fold increased risk of developing cardiovascular disease. This chapter focuses on the anti-diabetic and cardioprotective functions of plasma high-density lipoproteins (HDLs).
Blake J, Cochran +2 more
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Diabetes is a worldwide public health issue, with the number of cases expected to reach 642 million by 2040. Patients with diabetes are at a two- to four-fold increased risk of developing cardiovascular disease. This chapter focuses on the anti-diabetic and cardioprotective functions of plasma high-density lipoproteins (HDLs).
Blake J, Cochran +2 more
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2022
A wealth of evidence indicates that high-density lipoprotein assumes the unique antiatherosclerosis and other cardioprotective properties. Based on that, HDL-C has been considered as a promising therapy target to reduce the cardiovascular diseases.
Ke, Li, Xianwei, Xie, Yansong, Guo
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A wealth of evidence indicates that high-density lipoprotein assumes the unique antiatherosclerosis and other cardioprotective properties. Based on that, HDL-C has been considered as a promising therapy target to reduce the cardiovascular diseases.
Ke, Li, Xianwei, Xie, Yansong, Guo
openaire +2 more sources