Extended-release niacin increases anti-apolipoprotein A-I antibodies that block the antioxidant effect of high-density lipoprotein-cholesterol: the EXPLORE clinical trial. [PDF]
Extended-release niacin (ERN) is the most effective agent for increasing high-density lipoprotein-cholesterol (HDL-C). Having previously identified anti-HDL antibodies, we investigated whether ERN affected the antioxidant capacity of HDL and whether ERN ...
Alves, JD+6 more
core +1 more source
Synergistic effects of serum albumin and HDL cholesterol concentrations on serum oxidized LDL cholesterol concentration in obese individuals with normal glycoregulation and patients with type 2 diabetes mellitus [PDF]
Background/Aim. Serum albumin and high-density lipoprotein (HDL) cholesterol molecules have multiple physiological functions, including an antioxidant role in neutralizing the harmful effects of oxidized low-density lipoprotein (oxLDL).
Pejin Radoslav+6 more
doaj +1 more source
Effect of Addition of Methionine to Rice Protein on the Cholesterol and Lipoproteins Concentrations in Rats [PDF]
The effect of the addition of methionine to rice protein on the levels of plasma and lipoproteins cholesterol in relation to the casein were investigated in rats.
Jaefar Dhahir+2 more
doaj +1 more source
HDL cholesterol: reappraisal of its clinical relevance
BackgroundWhile several lines of evidence prove that elevated concentrations of low-density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its clinical consequences, high-density lipoproteins are still widely believed to
W. März+9 more
semanticscholar +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Weight loss surgery in adolescents corrects high-density lipoprotein subspecies and their function. [PDF]
Background/objectiveYouth with obesity have an altered high-density lipoprotein (HDL) subspecies profile characterized by depletion of large apoE-rich HDL particles and an enrichment of small HDL particles.
Davidson, WS+8 more
core +1 more source
Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. [PDF]
BACKGROUND: The relevance of blood lipid concentrations to long-term incidence of cardiovascular disease and the relevance of lipid-lowering therapy for cardiovascular disease outcomes is unclear.
Alver, M. (Maris)+86 more
core +10 more sources
Objective The Plants for Joints (PFJ) intervention, including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome–associated hip or knee osteoarthritis (MSOA) compared to usual care.
Carlijn A. Wagenaar+10 more
wiley +1 more source
Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. [PDF]
Lipoproteins isolated from normal human plasma can bind and neutralize bacterial lipopolysaccharide (LPS) and may represent an important mechanism in host defense against gram-negative septic shock. Recent studies have shown that experimentally elevating
Kane, JP+4 more
core +1 more source
Paraoxonase 1 as an important antiatherogenic agent
The inverse relationship between High Density Lipoproteins (HDL) level and risk of ischaemic heart disease was proved by many epidemiological studies. Although the main mechanism of antiatherogenic activity of HDL is a reverse transport of cholesterol ...
Ewa Lidia Krzewicka-Romaniuk+3 more
doaj +1 more source