Results 41 to 50 of about 108,215 (261)

Pathological complete response with immunotherapy and brachytherapy to 15 metastatic liver lesions in a single patient

Hepatic Oncology, 2022
Materials & methods: High dose rate interstitial brachytherapy (HDR-IBT) treatment plan for 15 metastatic liver lesions in a patient with pancreatic cancer was retrieved and analyzed for liver dose parameters and diaphragm dose.
Gokula Kumar Appalanaido, Muhamad Zabidi Ahmad, Syadwa Abdul Shukor, Alex Khoo Cheen Hoe, Manisekar K Subramaniam, Ang Soo Fan, Mohd Zahri Abdul Aziz   +6 more
doaj   +1 more source

Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics

Advanced Functional Materials, EarlyView.
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha, Yingshan Ma, Yong Nam An, Sung‐Un An, Hyeon Hak Jung, Suvi‐Tuuli Varjamo, Jiwon Yoo, Junho Min, Hanvit Kim, Faisal Ahmed, Sang Hoon Chae, Young Min Song, Weiwei Cai, Tawfique Hasan, Zhipei Sun, Dong‐Ho Kang, Hyeon‐Jin Shin, Yunyun Dai, Hoon Hahn Yoon   +18 more
wiley   +1 more source

Towards standardised cross-sectoral agreements for data depositing and data access in Trusted Research Environments: streamlined contracting to advance public benefit research. 

International Journal of Population Data Science
Objective  Trusted Research Environments (TREs) rely on Data Contributor Agreements (DCAs) and Data Access Agreements (DAAs) to bind organisations to terms and conditions in place to protect data.
Rachel Brophy, Cassie Smith, Andy Boyd, Pan UK Data Governance Steering Group   +3 more
doaj   +1 more source

The Disk Population of the Taurus Star-Forming Region

, 2010
We have analyzed nearly all images of the Taurus star-forming region at 3.6-24um that were obtained during the cryogenic mission of the Spitzer Space Telescope (46 deg^2) and have measured photometry for all known members of the region that are within ...
Allen, Andrews, André, Backman, Balona, Baraffe, Barrado y Navascués, Beck, Bontemps, Bourke, Briceño, Briceño, Briceño, Briceño, Brown, Burgasser, C. Espaillat, Calvet, Carpenter, Carpenter, Chabrier, Cruz, Cruz, Currie, Currie, Currie, D'Alessio, Dahm, Dahm, Damjanov, Dobashi, Downes, Duchêne, Dunham, D’Alessio, Ercolano, Espaillat, Espaillat, Espaillat, Espaillat, Evans, Fazio, Feigelson, Flaherty, Forrest, Furlan, Furlan, Furlan, Gautier, Gizis, Gutermuth, Gutermuth, Haisch, Hartigan, Hartmann, Hartmann, Herczeg, Hernández, Hernández, Hernández, Hernández, Hughes, Hughes, Ireland, K. L. Luhman, Kenyon, Kenyon, Kenyon, Kim, Kirkpatrick, Kirkpatrick, Kraus, L. Hartmann, Lada, Lada, Looper, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Luhman, Malfait, Mamajek, Mamajek, Marengo, Martín, Martín, Massarotti, Megeath, Megeath, Moitinho, Morrow, Motte, Motte, Muench, Muzerolle, N. Calvet, P. R. Allen, Prato, Preibisch, Prusti, Quillen, Rebull, Rieke, Rieke, Sicilia-Aguilar, Sicilia-Aguilar, Sicilia-Aguilar, Skrutskie, Slesnick, Song, Steffen, Walter, Watson, Webb, Werner, White, White, White, Wichmann, Zasowski   +132 more
core   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

HDR

, 2007
Synthèse de la ...
  +6 more sources

A brief review of low-dose rate (LDR) and high-dose rate (HDR) brachytherapy boost for high-risk prostate [PDF]

, 2019
For patients with unfavorable or high-risk prostate cancer, dose escalated radiation therapy leads to improved progression free survival but attempts to deliver increased dose by external beam radiation therapy (EBRT) alone can be limited by late ...
Baumann, Brian C, Fischer-Valuck, Benjamin W, Gay, Hiram A, Michalski, Jeff M, Patel, Sagar   +4 more
core   +1 more source

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

Advanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu, Ju‐Chan Park, Heesoo Uhm, Yong‐Woo Kim, Hyeon Woo Im, Sangsu Bae   +5 more
wiley   +1 more source