Results 61 to 70 of about 108,215 (261)

Constraining Emission Models of Luminous Blazar Sources

, 2009
Many luminous blazars which are associated with quasar-type active galactic nuclei display broad-band spectra characterized by a large luminosity ratio of their high-energy (gamma-ray) and low-energy (synchrotron) spectral components.
/Kipac, Menlo Park /Jagiellonian U., Astron. Observ. /SLAC, /KIPAC, Menlo Park /SLAC, /Warsaw, Copernicus Astron. Ctr., /Warsaw, Copernicus Astron. Ctr., Madejski, Greg, Moderski, Rafal, Nalewajko, Krzysztof, Sikora, Marek, Stawarz, Lukasz   +8 more
core   +1 more source

Building Community Amidst the Institutional Whiteness of Graduate Study: Black Joy and Maroon Moves in an Academic Marronage

Australian Journal of Social Issues, EarlyView.
ABSTRACT This article reflects on the construction of a supportive community of Black Afro‐diasporic graduate students and their supervisors researching issues relating to race in the field of education in Australia. It draws on the concept of marronage—a term rooted in the fugitive act of becoming a maroon, where enslaved people enacted an escape in ...
Hellen Magoi, Casianus Gemoh, Denise Chapman, Edmund Hypolite, Simon Angok, Melanie Baak, Joel Windle   +6 more
wiley   +1 more source

Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair

Scientific Reports, 2021
CRISPR–Cas proteins are RNA-guided nucleases used to introduce double-stranded breaks (DSBs) at targeted genomic loci. DSBs are repaired by endogenous cellular pathways such as non-homologous end joining (NHEJ) and homology-directed repair (HDR ...
Mollie S. Schubert, Bernice Thommandru, Jessica Woodley, Rolf Turk, Shuqi Yan, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig   +7 more
doaj   +1 more source

Adaptive Filters for 2-D and 3-D Digital Images Processing [PDF]

, 2012
Práce se zabývá adaptivními filtry pro vizualizaci obrazů s vysokým rozlišením. V teoretické části je popsán princip činnosti konfokálního mikroskopu a matematicky korektně zaveden pojem digitální obraz.
Martišek, Karel
core  

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Handwritten digit recognition: Comparative analysis of ML, CNN, vision transformer, and hybrid models on the MNIST dataset

Journal of Intelligent Systems
Handwritten digit recognition (HDR) remains challenging due to variations in writing styles. To address this challenge, this study comprehensively compares ML (ML) and deep learning (DL) models. We explored a variety of approaches.
Ben Noureddine Dhouha
doaj   +1 more source

Réparer la nature, est-ce bien raisonnable ? [PDF]

Sciences, Eaux & Territoires, 2017
Un problème se pose au gestionnaire qui souhaite préserver ou réhabiliter une zone humide : quel état de cette zone en perpétuelle évolution choisir ? Ce parti pris n’est pas anodin : il implique des notions de mémoire, d’héritage, de patrimoine.
DEREX, Jean-Michel
doaj  

On Improving the Pooling in HDR-VDP-2 towards Better HDR Perceptual Quality Assessment [PDF]

, 2014
International audienceHigh Dynamic Range (HDR) signals capture much higher contrasts as compared to the traditional 8-bit low dynamic range (LDR) signals.
Le Callet, Patrick, Narwaria, Manish, Perreira Da Silva, Matthieu, Pépion, Romuald   +3 more
core   +1 more source

Fourier and Gegenbauer expansions for a fundamental solution of the Laplacian in the hyperboloid model of hyperbolic geometry

, 2012
Due to the isotropy $d$-dimensional hyperbolic space, there exist a spherically symmetric fundamental solution for its corresponding Laplace-Beltrami operator.
Abramowitz M, Andrews G E, Beltrami E, Bers L, Byrd P F, Cohl H S, Cohl H S, Cohl H S, E G Kalnins, Erdélyi A, Erdélyi A, Fano U, Folland G B, Fox L, Gilbarg D, Gradshteyn I S, Grigor’yan A A, Grigor’yan A A, Grigor’yan A A, H S Cohl, Helgason S, Izmest’ev A A, Kalnins E G, Lee J M, Livio M, Losev A G, Magnus W, Morse P M, Olevskii˘ M N, Olver F W J, Olver F W J, Schoen R, Thurston W P, Trudeau R J, Vilenkin N Ja   +34 more
core   +2 more sources