Results 71 to 80 of about 15,184 (209)

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, Volume 32, Issue 6, Page 1397-1412, November/December 2026.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice

, 2017
Co-infection with hepatitis B (HBV) and D virus (HDV) is associated with the most severe course of liver disease. Interferon represents the only treatment currently approved.
Maria Buti, Katja Giersch, Maria Homs, Marc Lütgehetmann, Tassilo Volz, Maura Dandri, Lena Allweiss, Ansgar W. Lohse, Martina Helbig, Camille Sureau, Jörg Petersen, Teresa Pollicino, Giersch, Katja, Helbig, Martina, Buti, Maria, Sureau, Camille, Allweiss, Lena, Lütgehetmann, Marc, Lohse, Ansgar W., POLLICINO, Teresa, Dandri, Maura, Volz, Tassilo, Petersen, Jörg, Homs, Maria   +23 more
core   +1 more source

Assessing the diagnostic accuracy of serological tests for hepatitis delta virus diagnosis: a systematic review and meta-analysis

Scientific Reports
Hepatitis Delta Virus (HDV), a satellite virus of Hepatitis B virus, exacerbates liver damage in affected individuals. Screening for HDV antibodies in HBsAg positive patients is recommended, but the diagnostic accuracy of serological tests remains ...
Golda Ataa Akuffo, Serge Ouoba, Ko Ko, Chanroth Chhoung, Zayar Phyo, Ulugbek Khudayberdievich Mirzaev, Aya Sugiyama, Tomoyuki Akita, Junko Tanaka   +8 more
doaj   +1 more source

Prevalence of hepatitis D virus infection among patients with chronic hepatitis B infection in a tertiary care centre in Thailand

Scientific Reports, 2023
Knowledge about the epidemiology of hepatitis D virus (HDV) is essential for effective screening and management. Our study aimed to update the prevalence of HDV infection among patients with hepatitis B virus (HBV) infection at hepatology clinics in ...
Prooksa Ananchuensook, Sirinporn Suksawatamnuay, Panarat Thaimai, Nipaporn Siripon, Supachaya Sriphoosanaphan, Kessarin Thanapirom, Yong Poovorawan, Piyawat Komolmit   +7 more
doaj   +1 more source

Hepatic Steatosis in People With Chronic Hepatitis B in Africa: Prevalence, Correlates, and Clinical Significance

Journal of Viral Hepatitis, Volume 33, Issue 11, November 2026.
ABSTRACT To address data gaps around metabolic liver disease in Africa, within the Hepatitis B in Africa Collaborative Network (HEPSANET), we evaluated participants with chronic hepatitis B virus infection (CHB) for steatotic liver disease (SLD) using transient elastography with controlled attenuation parameter (CAP).
Freeman W. Chabala, Edford Sinkala, Alana T. Brennan, Amy Miskimon Goss, Lamin Bojang, Yusupha Samateh, Alexander J. Stockdale, Roger Sombie, Arouna Sessouma, Alice Nanelin Guingane, Juste Aristide Goungounga, Mohamed El‐Kassas, Eman Marwan, Ibrahima Diallo, Abdoul Sow, Edith Okeke, Attah Okwute, Hans Prozesky, Zahiera Ismail, Mark Sonderup, C. Wendy Spearman, Philippa C. Matthews, Judicaël Malick Tine, Maud Lemoine, Hailemichael Desalegn Mekonnen, Asgeir Johnannessen, Michael J. Vinikoor, on behalf of Hepatitis B in Africa Collaborative Network (HEPSANET), Alice Guingane, Roger Sombie, Asgeir Johannessen, Edith Okeke, Mohamed El‐Kassas, Gilles Wandeler, Ibrahima Diallo, Joan Rugemalila, Wendy Spearman, Hans Prozesky, Alex Stockdale, Maud Lemoine, Babatunde Duduyemi, Mary Afihene, Edford Sinkala, Asgeir Johannessen, Roger Sombie, Alex Stockdale, Alice Guingane, Michael Vinikoor, Edith Okeke, Maud Lemoine, Philippa Matthews, Wendy Spearman, Adria Ramirez   +52 more
wiley   +1 more source

HBV/HDV Coinfection

Clinics in Liver Disease, 2019
Chronic hepatitis D (CHD) results from an infection with the hepatitis B virus and hepatitis D virus (HDV). CHD is the most severe form of human viral hepatitis. Current treatment options consist of interferon alfa, which is effective only in a minority of patients. Study of HDV molecular virology has resulted in new approaches entering clinical trials,
Christopher, Koh, Ben L, Da, Jeffrey S, Glenn   +2 more
openaire   +3 more sources

The prevalence of HDV among HBsAg-positive populations with and without HIV-1 in China

International Journal of Infectious Diseases
Background: Existing research has provided evidence of changes in hepatitis delta virus (HDV) prevalence worldwide. This study aimed to investigate the prevalence and molecular characteristics of HDV to elucidate its spread in China.
Yan Wang, Guizhou Shen, Ruichao Lu, Jun Liu, Feng Zhang, Hui Wang, Weiping Cai, Fujie Zhang   +7 more
doaj   +1 more source

Hepatitis A Virus (HAV) Recurrence and De Novo Hepatitis A Acquired at Time of Liver Transplantation: Comparison of Graft HAV Infection and Viral Kinetics

Journal of Viral Hepatitis, Volume 33, Issue 11, November 2026.
ABSTRACT Hepatitis A virus (HAV) infection is an uncommon indication for liver transplantation, and donor‐derived or transfusion‐associated HAV infection is rare. Data describing HAV recurrence or early acquisition following liver transplantation, particularly with longitudinal quantitative viral kinetics, are limited.
David Mutimer, Elinor Latham, Sowsan F. Atabani, Samreen Ijaz   +3 more
wiley   +1 more source

Spontaneous Bilateral Vesical Artery Pseudoaneurysms Presenting With Massive Recurrent Hematuria and Obstructive Acute Kidney Injury: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Spontaneous development of vesical artery pseudoaneurysm (VA‐PA) as a cause of life‐threatening hematuria is very rare. Most of the existing reports are due to trauma or other types of pelvic surgeries/urological procedures. Incomplete hemostasis in these patients can lead to subsequent complications such as clot retention, severe blood loss ...
Dheeraj Kumar Alias Sailish, Amisha Kumari, Hadia Jamil, Sardar Ravi Singh, Muhammad Hassaan Javaid, Muddassir Khalid, Fred Segawa   +6 more
wiley   +1 more source

Virus‐Induced Genome Editing in the Parasitic Plant Phtheirospermum japonicum

Plant, Cell &Environment, EarlyView.
Hannes Ruwe, Freya Inger Kleinelanghorst, Victoria Zimmer, Thomas Spallek   +3 more
wiley   +1 more source