Results 71 to 80 of about 651,564 (257)

Head and neck cancer: molecular carcinogenesis

Annals of Oncology, 2005
To date it is widely accepted that an accumulation of genetic and epigenetic alterations in oncogenes and tumor suppressor genes forms the basis for the progression of a normal cell to a cancer cell, referred to as the process of multistep carcinogenesis.
Braakhuis, B. J.M., Brakenhoff, R. H., Leemans, C. R.   +2 more
openaire   +3 more sources

RAD51C – a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC) [PDF]

, 2014
INTRODUCTION: Head and neck squamous cell carcinomas (HNSSCs) are one of the leading causes of cancer-associated death worldwide. Although certain behavioral risk factors are well recognized as tumor promoting, there is very little known about the ...
Baldus, Stephan E., Balz, Vera, Freund, Marcel, Hanenberg, Helmut, Pakropa, Petra, Scheckenbach, Kathrin, Schipper, Jörg, Schäfer, Karl-Ludwig, Sproll, Christoph, Wagenmann, Martin   +9 more
core   +1 more source

Factors associated with delay in diagnosis of oral cancers

Cancer Treatment and Research Communications
Background: Oral cancer is one of the ten most common malignancies in the world and approximately 90 % of cases are OSCC. Despite the progress in available treatment modalities, the mortality of patients with OSCC has remained steadily high during the ...
Deepa Swaminathan, Nebu Abraham George, Shaji Thomas, Elizabeth Mathew Iype   +3 more
doaj   +1 more source

Lembo miofasciale di vasto laterale nella ricostruzione della lingua [PDF]

Acta Otorhinolaryngologica Italica, 2016
Nell'ultimo decennio il lembo antero-laterale di coscia (ALT) è diventato il lembo libero più utilizzato nella ricostruzione della lingua, dal momento che esso è caratterizzato da bassa morbidità a livello del sito donatore e da migliori risultati ...
R. Pellini, A. De Virgilio, G. Mercante, B. Pichi, V. Manciocco, P. Marchesi, F. Ferreli, G. Spriano   +7 more
doaj   +1 more source

Evaluation of shoulder disability questionnaires used for the assessment of shoulder disability after neck dissection for head and neck cancer [PDF]

, 2014
Background Several questionnaires have been used to evaluate shoulder disability after neck dissection. The purpose of this study was to review these measures and highlight their strengths and weaknesses. Methods A literature review was performed to
Angst, Angst, Angst, Beaton, Beaton, Bot, Breckenridge, Bushnell, Chepeha, Conboy, Constant, Desai, Getahun, Gliklich, Goldstein, Heijden, Hudak, Jamnik, John, Kirkley, Kirkley, Kirkley, Kocher, Marchese, McClure, Michener, Michener, Mokkink, Novak, Padua, Richards, Roach, Roy, Solway, Taylor, Winter   +35 more
core   +1 more source

The head and neck cancer immune landscape and its immunotherapeutic implications.

JCI Insight, 2016
Recent clinical trials have demonstrated a clear survival advantage in advanced head and neck squamous cell carcinoma (HNSCC) patients treated with immune checkpoint blockade.
Rajarsi Mandal, Y. Şenbabaoğlu, A. Desrichard, J. Havel, Martin G. Dalin, N. Riaz, Ken-Wing Lee, I. Ganly, A. Hakimi, T. Chan, L. Morris   +10 more
semanticscholar   +1 more source

Skip metastasis in papillary thyroid carcinoma is difficult to predict in clinical practice

BMC Cancer, 2017
Background Cervical lymph node metastases are very common in papillary thyroid cancer (PTC), and typically spread in a predictable stepwise fashion in clinical practice. However, lateral lymph node metastasis (LLNM) without central lymph node metastasis (
Xilin Nie, Zhou Tan, Minghua Ge
doaj   +1 more source

Oral and maxillofacial rehabilitation of head and neck cancer patients [PDF]

, 2009
The general aim of this paper was to gain insight into the effects of maxillofacial rehabilitation in head and neck cancer patients using implantretained prostheses regarding treatment planning, implant survival, treatment outcome and quality of life. In
Kocev, Pavle, Milosev, Vladimir, Miloseva, Lence   +2 more
core  

American college of radiology appropriateness criteria ® treatment of stage I T1 glottic cancer [PDF]

, 2014
Background Controversy surrounds the appropriate therapy for T1 glottic cancer. Both transoral endolaryngeal resection and radiation offer excellent local control and voice quality; some lesions are best addressed with resection and others with ...
Abdurehim, Agarwal, Akine, Bibby, Biel, Burke, Cellai, Cellai, Chera, Chera, Dey, Dinshaw, Fein, Foote, Ganly, Groome, Groome, Hardie, Hartl, Hartl, Harwood, Harwood, Higgins, Hintz, Hocevar-Boltezar, Holsinger, Izuno, Johansen, Le, Mahler, Mendenhall, Mills, Motta, Parsons, Pellini, Peretti, Pfister, Reddy, Remacle, Remacle, Roedel, Roh, Rosenthal, Rödel, Schrijvers, Schwartz, Shah, Silver, Silver, Sjögren, Sjögren, Smith, Spayne, Teshima, Vilaseca, Voet, Yamazaki   +56 more
core   +1 more source

Salvage Reconstructive Surgery During Nivolumab Therapy for a Patient With Hypopharyngeal Cancer

Clinical Medicine Insights: Case Reports, 2020
Objectives: Nivolumab, a fully IgG4-programmed death-1 inhibitor antibody, led to improved overall survival compared with single-agent therapy in patients with platinum-refractory recurrent head and neck cancers.
Nayuta Tsushima, Takeshi Shinozaki, Takao Fujisawa, Toshifumi Tomioka, Wataru Okano, Masakazu Ikeda, Makoto Tahara, Takuya Higashino, Ryuichi Hayashi   +8 more
doaj   +1 more source