Results 121 to 130 of about 229,667 (331)

Trend Analysis of Head and Neck Neoplasms between 2012-2018 in Patients Residing in Al-Madinah, Saudi Arabia: A Retrospective Study. [PDF]

Eur J Dent, 2021
Alsharif MT, Alsharif AT, Krsoum MA, Aljohani MA, Qadiri OM, Alharbi AA, Al-Maweri SA, Warnakulasuriya S, Kassim S.   +8 more
europepmc   +1 more source

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Solitary Fibrous Tumor of the Supraclavicular Region

Turkish Archives of Otorhinolaryngology, 2014
Solitary fibrous tumors of the head and neck are extremely rare, slow-growing, and generally asymptomatic benign neoplasms. To the best of our knowledge, only 153 cases of solitary fibrous tumors in the head and neck have been previously reported in the ...
Çağatay Han Ülkü, Yasin Kürşad Varsak, Osman Yılmaz   +2 more
doaj   +1 more source

Head and neck neoplasms.

Canadian family physician Medecin de famille canadien, 2013
Tumours of the head and neck show a wide spectrum of natural behaviour ranging from the most benign to the extremely lethal. Investigative techniques are of limited usefulness. History and physical examination are the foundations for diagnosis, though ultimate proof rests on surgical biopsy. The author of this article discusses the more common head and
openaire   +1 more source

Historical Landmarks in Head and Neck Cancer Surgery

, 1999
The term "head and neck cancer" usually refers to neoplasms involving the upper aerodigestive tract and other related areas (but not including tumors of the brain; brain tumors fall under the domain of the neurosurgeon).
Shedd, Donald P.
core  

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

Advanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang, Ting Shen, Yanfang Qiu, Wei Zhang, Ziran Zheng, Jiayi Sun, Yuedi Yao, Mianfeng Yao, Jiang Li   +8 more
wiley   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Panendoscopy as a screening procedure for simultaneous primary tumors in head and neck cancer

, 1996
Head and neck cancer is often associated with second primary neoplasms. These cancers most commonly involve other regions of the head and neck, esophagus, and lung. The majority of cases are also squamous cell carcinomas.
Van Cauwenberge, Paul, Dhooge, IngeborgGE34UZGent8010008783130000-0002-5915-1079F4A8B1EE-F0ED-11E1-A9DE-61C894A0A6B4, Van Cauwenberge, PaulUGent801000413319979776493590F9436D48-F0ED-11E1-A9DE-61C894A0A6B4, De Vos, Martine, Albers, FWJ, DHOOGE, IJ, DeVos, M, VAN CAUWENBERGE, PB, Dhooge, Ingeborg, De Vos, MartineGE35001959948755801000395535F3EBA27A-F0ED-11E1-A9DE-61C894A0A6B4, ALBERS, F, VanCauwenberge, PB   +11 more
core   +1 more source

Critical Update on Malignant Salivary Gland Neoplasms

, 2017
Salivary gland neoplasms are relatively rare tumors with a wide range of biologic behavior. Early low-grade malignancies could be adequately treated with surgery alone, while larger locally advanced tumors will require adjuvant radiation therapy.
Natalya Chernichenko
core   +1 more source

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

Advanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi, Timothy P. Padera, Lance L. Munn   +2 more
wiley   +1 more source