Results 111 to 120 of about 216,489 (301)

Epidemiology and Aetiology of Head and Neck Cancers

open access: yes, 2016
Malignant neoplasms of the head and neck are among the most common in the world and constitute a major public health problem in most countries. Over 90 % of these are squamous cell carcinomas arising in the mucous membranes of the upper aerodigestive ...
Hemantha K. Amarasinghe   +5 more
core   +1 more source

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

open access: yesAdvanced Science, EarlyView.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku   +4 more
wiley   +1 more source

Historical Landmarks in Head and Neck Cancer Surgery

open access: yes, 1999
The term "head and neck cancer" usually refers to neoplasms involving the upper aerodigestive tract and other related areas (but not including tumors of the brain; brain tumors fall under the domain of the neurosurgeon).
Shedd, Donald P.
core  

Prognostic factors in carcinoma of the external auditory canal

open access: yes, 1997
Background: Carcinomas of the external auditory canal are rare neoplasms (
L. P. Kowalski   +5 more
core   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

open access: yesAdvanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh   +22 more
wiley   +1 more source

Predisposing Factors and Clinico-Pathological Presentation of Malignant Lesions of the Oro-Facial Region Among Patients Attending the Muhimbili National Hospital in Dar-es-Salaam, Tanzania [PDF]

open access: yes, 2011
The oro-facial region is made up of a complex anatomical relationship of structures of which may be a source of development of malignant lesions. Often, patients present at the oral and maxillofacial unit of Muhimbili National Hospital with a variety of ...
Berege, Gemma Z
core  

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

open access: yesAdvanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo   +10 more
wiley   +1 more source

Evaluation of prognostic factors of head and neck squamous cell carcinomas in Iranian patients: A narrative review [PDF]

open access: yesJournal of Oral Health and Oral Epidemiology
BackgroundHead and neck squamous cell carcinoma (HNSCC) represents the largest proportion of head and neck cancers (HNCs). Despite new treatment modalities, the 5-year survival rate has not improved much.
Mahdieh Rajabi-Moghaddam   +1 more
doaj  

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