Results 101 to 110 of about 236,855 (311)

Metastatic cervical paravertebral solitary fibrous tumor detected by fluorodeoxyglucose positron emission tomography-computed tomography. [PDF]

open access: yes, 2018
Solitary fibrous tumor/hemangiopericytomas (SFT/HPC) are soft tissue tumors that can arising from the abomen, pleura, head and neck, or extremities.
Aparici, Carina Mari   +4 more
core   +2 more sources

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Review of MicroRNA Deregulation in Oral Cancer. Part I

open access: yeseJournal of Oral Maxillofacial Research, 2011
Objectives: Oral cancer is the sixth most common malignancy worldwide. Cancer development and progression requires inactivation of tumour suppressor genes and activation of proto-oncogenes.
Antonia Kolokythas   +2 more
doaj  

Head and neck cancer mortality by gender, region and ethnicity: a population-based study in BrazilResearch in context

open access: yesThe Lancet Regional Health. Americas
Summary: Background: Brazil exhibits the highest mortality rates for oral cavity (OCC), oropharyngeal (OPC), and laryngeal (LC) cancers in South-America.
Matheus de Abreu   +2 more
doaj   +1 more source

Ossifying fibromyxoid tumor of the oral cavity: rare case report and long-term follow-up

open access: yesAutopsy and Case Reports, 2021
Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal soft tissue benign neoplasm with an uncertain line of differentiation, which arises most frequently in extremities.
Maria Eduarda Pérez-de-Oliveira   +5 more
doaj  

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Evaluation of prognostic factors of head and neck squamous cell carcinomas in Iranian patients: A narrative review [PDF]

open access: yesJournal of Oral Health and Oral Epidemiology
BackgroundHead and neck squamous cell carcinoma (HNSCC) represents the largest proportion of head and neck cancers (HNCs). Despite new treatment modalities, the 5-year survival rate has not improved much.
Mahdieh Rajabi-Moghaddam   +1 more
doaj  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

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