Results 81 to 90 of about 198,685 (310)

Role of Post-Treatment 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Patients Receiving Definitive Chemoradiation for Locally Advanced Head and Neck Squamous Cell Carcinomas [PDF]

, 2022
Jae-Joon Kim, Sang-Bo Oh, Ki Sun Jung, Kwonoh Park, Seong‐Jang Kim, Yongkan Ki, Jin‐Choon Lee, So Yeon Oh   +7 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Supplementary Data from A Phase II Trial of Pembrolizumab and Vorinostat in Recurrent Metastatic Head and Neck Squamous Cell Carcinomas and Salivary Gland Cancer

, 2023
Cristina P. Rodriguez, Qian Wu, Jenna Voutsinas, Jonathan R. Fromm, Xiuyun Jiang, Venu G. Pillarisetty, Sylvia M. Lee, Rafael Santana-Dávila, Bernardo H. L. Goulart, Christina S. Baik, Laura Q.M. Chow, Keith D. Eaton, Renato Martins   +12 more
openalex   +1 more source

Supplementary Tables 1 - 4 from The Dual Pathway Inhibitor Rigosertib Is Effective in Direct Patient Tumor Xenografts of Head and Neck Squamous Cell Carcinomas [PDF]

, 2023
Ryan T. Anderson, Stephen B. Keysar, Daniel W. Bowles, Magdalena J. Glogowska, David P. Astling, J. Jason Morton, Phuong A. Le, Adrian Umpierrez, Justin R. Eagles-Soukup, Gregory N. Gan, Brian W. Vogler, Daniel Sehrt, Sarah M. Takimoto, Dara L. Aisner, François Wilhelm, Barbara Frederick, Marileila Varella-Garcia, Aik Choon Tan, Antonio Jimeno   +18 more
openalex   +1 more source

Prognostic Value of Tumor-Infiltrating Lymphocytes in Head and Neck Squamous Cell Carcinoma.

JAMA Otolaryngology - Head and Neck Surgery, 2019
Importance Biomarkers that reflect prognosis and cellular immunity in patients with head and neck squamous cell carcinoma (HNSCC) are a prerequisite for improving individualized treatment that limits the intensity and morbidity of conventional treatment ...
M. Spector, E. Bellile, Lahin M. Amlani, Katie R. Zarins, Joshua D Smith, J. Brenner, L. Rozek, Ariane Nguyen, Daffyd G. Thomas, J. Mchugh, Jeremy M. G. Taylor, G. Wolf, Neck Spore Program   +12 more
semanticscholar   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

Primary cilia-associated signalling in squamous cell carcinoma of head and neck region

Frontiers in Oncology
Squamous cell carcinoma (SCC) of the head and neck originates from the mucosal lining of the upper aerodigestive tract, including the lip, tongue, nasopharynx, oropharynx, larynx and hypopharynx. In this review, we summarise what is currently known about
Iveta Putnová, Iveta Putnová, Barbora Moldovan Putnová, Barbora Moldovan Putnová, Pavel Hurník, Pavel Hurník, Pavel Hurník, Jan Štembírek, Jan Štembírek, Marcela Buchtová, Marcela Buchtová, Petra Kolísková, Petra Kolísková   +12 more
doaj   +1 more source

Cell-free mitochondrial DNA copy number variation in head and neck squamous cell carcinoma: A study of non-invasive biomarker from Northeast India

Tumor Biology, 2017
Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the Northeast Indian population toward higher susceptibility to develop head and neck squamous cell ...
Manish Kumar, Shilpee Srivastava, Seram Anil Singh, Anup Kumar Das, Ganesh Chandra Das, Bishal Dhar, Sankar Kumar Ghosh, Rosy Mondal   +7 more
doaj   +1 more source

Impact of Circular Stapler Size on Short‐Term Outcomes and Long‐Term Quality of Life After McKeown Esophagectomy

Annals of Gastroenterological Surgery, EarlyView.
In this study, we investigated the impact of circular stapler size on both short‐term outcomes and long‐term QOL after McKeown esophagectomy. We revealed that short‐term outcomes, including anastomotic leakage and stenosis, did not differ between patients who underwent anastomosis with a 21 mm stapler and those with a 23 mm stapler.
Suguru Maruyama, Katsutoshi Shoda, Yoshihiko Kawaguchi, Ryo Saito, Wataru Izumo, Kensuke Shiraishi, Shinji Furuya, Hidetake Amemiya, Hiromichi Kawaida, Daisuke Ichikawa   +9 more
wiley   +1 more source

Role of E-cadherin and β-catenin in head and neck squamous cell carcinoma

Сибирский онкологический журнал
Aim of the study: to present and summarize current data on the prognostic value of E-cadherin and β-catenin markers for head and neck squamous cell carcinoma, as well as to substantiate the potential benefit from implementing research results into ...
A. A. Petrova, S. I. Samoylova, L. V. Magomedkerimova, S. A. Parts, I. V. Reshetov   +4 more
doaj   +1 more source