Results 101 to 110 of about 118,755 (255)

Expert consensus on gepants for acute and preventive treatment of migraine in Thailand

The Journal of Headache and Pain
Introduction Gepants, a calcitonin gene-related peptide (CGRP) receptor antagonist, is a class of migraine therapeutic options with extensive evidence supporting a favorable efficacy and safety profile. However, as a novel class of medication in Thailand,
Prakit Anukoolwittaya, Wanakorn Rattanawong, Kiratikorn Vongvaivanich, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Thaninjitra Poonpedpun, Pannathat Soontrapa, Kanokrat Suwanlaong, Kannikar Kongbunkiat, Surasak Komonchan, Petcharat Dusitanond, Chutithep Teekaput, Nopdanai Sirimaharaj, Nadolporn Yuvasilp, Surat Tanprawate   +14 more
doaj   +1 more source

Clinical profile of SUNCT/SUNA in Japan: A clinic-based study

Cephalalgia Reports, 2019
Objectives: This study aimed to report the clinical profiles of patients with short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT)/short-lasting unilateral neuralgiform headache attacks with cranial ...
Shoji Kikui, Junichi Miyahara, Hanako Sugiyama, Kentaro Yamakawa, Yoshihiro Kashiwaya, Kumiko Ishizaki, Daisuke Danno, Takao Takeshima   +7 more
doaj   +1 more source

Abnormal neuromuscular transmission in cluster headache

, 2003
Objective.-To identify and investigate any dysfunction of neuromuscular transmission in episodic cluster ...
ERTAS, M, Baslo, Mehmet Barış
core   +1 more source

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

Advanced Science, EarlyView.
Bilateral temporal accelerated 40‐Hz tACS improves cognitive function in patients with Alzheimer's disease. Resting‐state fNIRS identifies treatment‐related increases in frontotemporoparietal functional connectivity, which are associated with cognitive improvement. ABSTRACT The temporal lobes are key hubs for memory and cognition.
Rong Guo, Xingxing Li, Chenjun Zou, Chao Zheng, Xiaohong Wu, Xuechao Lu, Jiaying Yan, Junfang Zhang, Xiaoyan Luo, Shiwei Ye, Dongsheng Zhou   +10 more
wiley   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Cluster headache and rare-disease classification in Brazil: a systematic review and policy perspective [PDF]

BackgroundCluster headache is a highly disabling trigeminal autonomic cephalalgia associated with substantial diagnostic delay, severe pain-related disability, and limited access to evidence-based treatments.
Ivy Liger Riso, Welber Sousa Oliveira, Arão Belitardo de Oliveira, Erlene Roberta Ribeiro dos Santos, Caio Vinicius de Meira Grava Simioni, Mauro Eduardo Jurno, Elder Machado Sarmento, Otávio Augusto de Oliveira Franco, Vanise Grassi, Mateus Franco, Mario Fernando Prieto Peres, Vitoria Acar, Grassi, Vanise, Acar, Vitoria, Oliveira, Arão Belitardo de, Oliveira, Welber Sousa, Riso, Ivy Liger, Jurno, Mauro Eduardo, Simioni, Caio Vinicius de Meira Grava, Franco, Mateus, Peres, Mario Fernando Prieto, Santos, Erlene Roberta Ribeiro dos, Sarmento, Elder Machado, Franco, Otávio Augusto de Oliveira   +23 more
core   +1 more source

Chrysanthemum Morifolium–Derived Nanovesicles Reduce Lactate‐Associated Histone Lactylation and Modulate Microglia‐Mediated Neuroinflammation in Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
When used to treat sepsis‐associated encephalopathy, Chrysanthemum morifolium–derived nanovesicles can inhibit the H3K18la/NF‐κB axis to regulate microglia‐mediated neuroinflammation. ABSTRACT Sepsis‐associated encephalopathy (SAE)—a complication of the central nervous system in patients with sepsis—markedly diminishes cognitive functions and is linked
Kaiqiang Li, Xuling Luo, Xiaoting Zhang, Chengwen He, Wei Xu, Aibo Xu, Shushan Hua, Liping Wang, Liang Ma, Ke Hao, Youmin Ying, Zhen Wang   +11 more
wiley   +1 more source

Perceptions, understandings and experiences of cluster headache patients in the north of England: a qualitative study

, 2015
Background: Very few qualitative studies on cluster headache have been conducted. As a result we have little in-depth understanding of the perceptions and experiences of cluster headache patients and the health professionals who treat them.
Ahmed, F., Goadsby, P. J., Quarshie, V., Paemeleire, K., Dikomitis, L.   +4 more
core  

Extreme Weather Events and Consumer Food Responses

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study investigates consumer food responses to Hurricanes Helene and Milton, which affected a swath of the Southeastern U.S. in 2024. Using representative consumer survey data from six affected states, we analyze 10 distinct food responses classified into ex ante and ex post responses, and examine their associations with food insufficiency
Ahmad Zia Wahdat, Joseph Balagtas
wiley   +1 more source

Clinical Spectrum of Reversible Cerebral Vasoconstriction Syndrome With and Without Angiographic Vasoconstriction: A Retrospective Study of 84 Hospitalized Patients

Brain and Behavior
Objective To determine whether patients with reversible cerebral vasoconstriction syndrome (RCVS) without demonstrable vasoconstriction differ clinically from those with angiographically confirmed vasoconstriction.
Katsuya Takeuchi, Shoji Kikui, Yoshiki Matsumoto, Kenji Murakata, Hanako Sugiyama, Kuniko Ota, Daisuke Danno, Yoshihiro Kashiwaya, Takao Takeshima   +8 more
doaj   +1 more source