Results 201 to 210 of about 118,755 (255)
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé +12 more
wiley +1 more source
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Pediatric Annals, 2021
Headaches are common in the pediatric population and can cause significant distress to the patient and their family. The ability of pediatricians to appropriately diagnose and differentiate headaches is important to guide management. This article reviews the epidemiology, classification, and treatment of headaches, including migraines.
openaire +2 more sources
Headaches are common in the pediatric population and can cause significant distress to the patient and their family. The ability of pediatricians to appropriately diagnose and differentiate headaches is important to guide management. This article reviews the epidemiology, classification, and treatment of headaches, including migraines.
openaire +2 more sources
Clinical Obstetrics and Gynecology, 1995
An attempt has been made to provide an overview of headache management for the primary healthcare provider for women. No attempt has been made to delineate for the clinician all care related to the difficult-to-manage headache patient, but at the same time, information has been provided that should assist the clinician in treating this common disorder.
+7 more sources
An attempt has been made to provide an overview of headache management for the primary healthcare provider for women. No attempt has been made to delineate for the clinician all care related to the difficult-to-manage headache patient, but at the same time, information has been provided that should assist the clinician in treating this common disorder.
+7 more sources
Seminars in Neurology, 2011
Headache is one of the most common complaints among patients presenting to an outpatient neurology practice. The evaluation, diagnosis, and treatment of headache can be rather cumbersome and at times quite challenging for even the most seasoned neurologist. Many complex issues that although not causative, can play an exacerbating role in the genesis of
Paul G, Mathew, Ivan, Garza
openaire +2 more sources
Headache is one of the most common complaints among patients presenting to an outpatient neurology practice. The evaluation, diagnosis, and treatment of headache can be rather cumbersome and at times quite challenging for even the most seasoned neurologist. Many complex issues that although not causative, can play an exacerbating role in the genesis of
Paul G, Mathew, Ivan, Garza
openaire +2 more sources
Seminars in Neurology, 2016
Headache disorders are primarily managed in an outpatient setting; therefore, the authors focus on the primary headache disorders that comprise the bulk of clinical practice. Red flags for secondary headaches that may be more commonly encountered in clinic are briefly discussed.
Amy R, Tso, Peter J, Goadsby
openaire +2 more sources
Headache disorders are primarily managed in an outpatient setting; therefore, the authors focus on the primary headache disorders that comprise the bulk of clinical practice. Red flags for secondary headaches that may be more commonly encountered in clinic are briefly discussed.
Amy R, Tso, Peter J, Goadsby
openaire +2 more sources
The American Journal of Medicine, 2018
Headache, an almost universal human experience, is one of the most common complaints encountered in medicine and neurology. Described and categorized since antiquity, with the first classification by Aretaeus of Cappadocia, other classifications followed.
Paul Rizzoli, William J. Mullally
openaire +2 more sources
Headache, an almost universal human experience, is one of the most common complaints encountered in medicine and neurology. Described and categorized since antiquity, with the first classification by Aretaeus of Cappadocia, other classifications followed.
Paul Rizzoli, William J. Mullally
openaire +2 more sources