Objective Clinically relevant Alzheimer's disease co‐pathology is common in Lewy body disorders. Plasma P‐tau217 is a sensitive biomarker for amyloid and tau pathology in Alzheimer's disease. The objective was to determine if plasma P‐tau217 associates with Alzheimer's disease co‐pathology and cognition in Lewy body disorders. Methods Participants had (
Thomas F. Tropea +20 more
wiley +1 more source
Restless legs syndrome and sleep quality in children with migraine and tension-type headache. [PDF]
Altın H, Ay F, Kutluk M.
europepmc +1 more source
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng +3 more
wiley +1 more source
Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study. [PDF]
Orr SL +12 more
europepmc +1 more source
AI‐Driven Mapping of Seizure Spread Patterns
Objective The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure analysis with clinical practice, leverage deep learning to standardize seizure annotations that varies among physicians, and understand ...
Andrew Y. Revell +13 more
wiley +1 more source
Bridging the gap in headache care: a qualitative needs assessment for primary care education in Indonesia. [PDF]
Madjid IS +11 more
europepmc +1 more source
Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease
Objective Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.
Patricia Zvarova +27 more
wiley +1 more source
Eptinezumab With Patient Education for Chronic Migraine and Medication-Overuse Headache: The Randomized, Placebo-Controlled RESOLUTION Trial. [PDF]
Jensen RH +13 more
europepmc +1 more source
The Dynamics of Neurofilament Light Chain in Spinal Muscular Atrophy
Objective Newborn screening (NBS) for spinal muscular atrophy (SMA) facilitates early diagnosis and treatment for affected individuals. However, fluid biomarkers that provide early insights into disease activity and outcomes in a neonatal cohort and those unable to access (due to reimbursement criteria) or deferring immediate treatment are lacking ...
Arlene D'Silva +13 more
wiley +1 more source
Efficacy of <i>Petasites hybridus</i> in migraine prophylaxis: the first real-world study. [PDF]
Silva-Néto RP.
europepmc +1 more source

