Results 71 to 80 of about 92,559 (293)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A STOCHASTIC APPROACH TO EVALUATE THE RELIABILITY OF URBAN PASSENGER TRANSPORTATION SERVICES [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2017
An approach to estimate the reliability of urban passenger transport from the passengers' viewpoint has been presented, in which the parameter to be investigated is the fixed-route headway.
D. Kopytkov
doaj  

Real-Time Estimation of the Distribution of Brake Response Times for an Individual Driver Using Vehicular Ad Hoc Network

, 2014
Adapting the functioning of the collision warning systems to the specific drivers' characteristics is of great benefit to drivers. For example, by customizing collision warning algorithms we can minimize false alarms, thereby reducing injuries and deaths
Pishro-Nik, Hossein, Rakhshan, Ali, Ray, Evan   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Reassessing desired time headway as a measure of car-following capability: Definition, quantification, and associated factors

Communications in Transportation Research
The desired time headway is often used to incorporate human behavior in car-following (CF) models by treating it as a measure of driver capability in car-following interactions, which is latent and cannot be directly observed.
Shubham Parashar, Zuduo Zheng, Andry Rakotonirainy, Md Mazharul Haque   +3 more
doaj   +1 more source

Congested Traffic States in Empirical Observations and Microscopic Simulations

, 2000
We present data from several German freeways showing different kinds of congested traffic forming near road inhomogeneities, specifically lane closings, intersections, or uphill gradients. The states are localized or extended, homogeneous or oscillating.
A. Hennecke, A. Reuschel, Ansgar Hennecke, B. Persaud, B. S. Kerner, B. Tilch, B.S. Kerner, B.S. Kerner, B.S. Kerner, B.S. Kerner, B.S. Kerner, B.S. Kerner, B.S. Kerner, C. F. Daganzo, C.F. Daganzo, D. Helbing, D. Helbing, D. Helbing, D. Helbing, D. Helbing, D. Helbing, D. Helbing, D.C. Gazis, D.C. Gazis, D.E. Wolf, Dirk Helbing, E. Ben-Naim, F.L. Hall, G.F. Newell, H.Y. Lee, H.Y. Lee, J. Treiterer, K. Nagel, L.C. Edie, L.D. Howe, M. Bando, M. Cremer, M. Cremer, M. Muramatsu, M. Treiber, M. Treiber, M. Treiber, M.J. Lighthill, Martin Treiber, O. Biham, P.G. Gipps, P.G. Gipps, R. Barlovic, R. Herman, R.D. Kühne, R.E. Chandler, S. Krauß, S. Smulders, T. Nagatani, V. Shvetsov   +54 more
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Disaggregate Inter-Urban Mode Choice Models: A review of British Evidence with special Reference to Cross Elasticities. [PDF]

, 1997
The research reported in this paper forms part of EPSRC project GRK52522 entitled 'National Multi-Modal Travel Forecasts'. The principal aim of this project is to develop a set of national and regional travel demand forecasts by land-based modes.
Wardman, M.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source