Results 71 to 80 of about 8,429 (258)
MathematicsThe capacity of transport infrastructure is one of the very important tasks in transport engineering, which depends mostly on the geometric characteristics of road and headway analysis.
Dejan Andjelković +5 more
doaj +1 more source
Capacity Estimation for On-Ramp Merging Section of Urban Expressway Based on Time Headway Loss
Discrete Dynamics in Nature and Society, 2014 This paper proposes a model for estimating capacity of on-ramp merging section of urban expressway based on dynamics and gap acceptance theory, considering lane-changing processes and time headway loss.
Xing-jian Xue, Feng Shi, Qun Chen
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Bicycle Headway Modeling and Its Applications
Transportation Research Record: Journal of the Transportation Research Board, 2016 Little is known about the microscopic operations of bicycle traffic. This lack of knowledge makes it difficult to design and to analyze facilities that are also used by cyclists, as well as to assess their efficiency and safety. This paper puts forward a novel composite headway model for bicycle flows.
Hoogendoorn, S.P. (author) +1 more
openaire +4 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Research on an Intelligent Scheduling Method Based on GCN-AM-LSTM for Bus Passenger Flow Prediction
Applied SciencesWith the acceleration of urbanization, public transit systems face prominent challenges, including insufficient passenger flow prediction accuracy and low scheduling efficiency.
Xiaolei Ji +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Establishment of Passenger Car Equivalent (PCE) Values for Urban Intersections Using Drones
Future TransportationPassenger Car Equivalent (PCE) factors are widely used to convert heterogeneous traffic streams into equivalent homogeneous flow rates for the design and analysis of roads and intersections.
Pramodh Senanayake +3 more
doaj +1 more source