Results 51 to 60 of about 8,429 (258)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Headway generation with ROBERTO [PDF]
WIT Transactions on The Built Environment, 2010 This paper on the use of the computer program ROBERTO for generating headway times is from the proceedings of the 12th International Conference on Computer System Design and Operation in Railways and Other Transit Systems, held in Beijing, China, in 2010.
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
ModellingEnergy-efficient operation of railway systems is of great importance for both environmental and economic reasons. Minimizing net energy consumption helps to achieve such energy-efficient operation.
Ahmed Y. Zakariya +2 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Communications in Transportation ResearchThe desired time headway is often used to incorporate human behavior in car-following (CF) models by treating it as a measure of driver capability in car-following interactions, which is latent and cannot be directly observed.
Shubham Parashar +3 more
doaj +1 more source
A STOCHASTIC APPROACH TO EVALUATE THE RELIABILITY OF URBAN PASSENGER TRANSPORTATION SERVICES [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2017 An approach to estimate the reliability of urban passenger transport from the passengers' viewpoint has been presented, in which the parameter to be investigated is the fixed-route headway.
D. Kopytkov
doaj
Ain Shams Engineering Journal, 2018 The present paper deals with optimizing optimal operation interaction for GCUM 1st and 2nd lines by proposing a methodology based on field survey of travel time, actual headway, passenger waiting time, alighting and boarding passengers to determine the ...
Mai M Eldeeb +3 more
doaj +1 more source