Results 121 to 130 of about 53,166 (277)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Measuring Subjective Wellbeing for Public Policy: Recommendations on Measures [PDF]
The measurement of wellbeing is central to public policy. There are three uses for any measure: 1) monitoring progress; 2) informing policy design; and 3) policy appraisal.
Richard Layard +2 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Wellbeing for children with a disability in New Zealand: A search for meaning by Maree Kirk
, 2006 This thesis explores the meaning of wellbeing for children with a disability in New Zealand, an area of social policy that has been largely unexamined.
Kirk, Maree Louise
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Working Together: Aboriginal and Torres Strait Islander Mental Health and Wellbeing Principles and Practice (First Edition) [PDF]
, 2010 Working Together: Aboriginal and Torres Strait Islander Mental Health and Wellbeing Principles and Practice (2nd Edition) edited by Pat Dudgeon, Helen Milroy and Roz Walker, is available here: https://www.telethonkids.org.au/our-research/early ...
Walker, Roz, Dudgeon, Pat, Purdie, Nola
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Renegotiating Work-Home Boundaries: Reconciliations of Remote Work and School During COVID-19
Nordic Journal of Working Life StudiesThis article contributes to understanding the radical transformation of everyday lives when parents’ remote work and children’s remote school were reconciled in homes during the early moments of the COVID-19 pandemic in 2020.
Mari Karhu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Entrepreneurial Crafting for Well-Being
Nordic Journal of Working Life StudiesEntrepreneurs in Nordic countries and elsewhere in Europe are often in precarious positions compared to salaried employees; they are outside organized occupational health care systems and solely responsible for their own well-being.
Salla Ahola, Kirsi Heikkilä-Tammi
doaj +1 more source