Results 101 to 110 of about 53,166 (277)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Ethical Infrastructure and Successful Handling of Workplace Bullying
Antecedents and consequences of workplace bullying are well documented. However, the mea- sures taken against workplace bullying, and the effectiveness of such measures, have received less attention.
Kari Einarsen +4 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The promotion of wellbeing: A primer for policymakers
There is growing international interest among policymakers in the promotion of wellbeing as an objective of public policy. Recent advances in the definition and measurement of wellbeing are giving rise to an increasingly detailed picture of the factors
Rablen, MD
core
Reach and Recruitment of Microentrepreneurs: Lessons from a Finnish Health Promotion Intervention
Even though entrepreneurial work is stressful, health promotion interventions are seldom targeted at entrepreneurs, and we know little about how to reach and recruit this hard-to-reach group to such studies.
Jaana-Piia Mäkiniemi +10 more
doaj
Young People’s Attitudes to Attractive Work, During and After Upper Secondary School
Attractive work has been defined as a job position which an individual wants, where the employee experiences job stability and where employee identification and dedication are fostered.
Ing-Marie Andersson +3 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Health and wellbeing in a deep plan office space
This research tracks public sector employees as they move from a 1960s office building into a purpose-built, environmentally sound, office accommodation.
Brown, Guy, Holmes, John, Capper, Graham
core

