Results 81 to 90 of about 20,327,512 (268)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Person environment relationships to health and wellbeing: An integrated approach [PDF]

, 2006
It is widely acknowledged that a strong relationship exists between physical environments and human health and wellbeing. More specifically, various dimensions of person environment (PE) relationships have been studied relating to the psychological ...
Franz, Jill M., Smith, Dianne J., Suresh, Mini   +2 more
core  

Hospital Mergers in Norway: Employee Health and Turnover to Three Destinations

Nordic Journal of Working Life Studies, 2017
This article investigates the probability of turnover to three destinations following hospital merg- ers: within the hospital sector, out of the hospital sector, and out of work.
Mari Holm Ingelsrud
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Lost in Translation-the Practice of Decoupling Work Environment Policy

Nordic Journal of Working Life Studies
Although companies and top managers claim that the work environment is a high priority, imple­menting such policies across organizational levels remains a challenge. In this regard, the Greenlandic labor market is no exception.
Søren Voxted, Anne Lise Kappel, Peter Hasle   +2 more
doaj   +1 more source

Paid Sick Leave as a Means to Reduce Sickness Presenteeism Among Physicians

Nordic Journal of Working Life Studies, 2017
Recurrent international data show that physicians often attend work while ill, termed sickness presenteeism. The current study investigated if sickness presenteeism scores among European physicians varied according to national paid sick leave legislation.
Ingrid Steen Rostad, Ann Fridner, Marie Gustafsson Sendén, Lise Tevik Løvseth   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Health & Wellbeing Division operational plan 2016

, 2016
This is the third Operational Plan for the Health and Wellbeing Division since its establishment in 2013. It continues the successful advancement of key priorities set out in previous plans in areas such as the implementation of the Healthy Ireland ...
Health & Wellbeing Division. Health Service Executive
core  

Work, Sickness, Absence, and Identity-Work

Nordic Journal of Working Life Studies, 2013
This article explores how a group of industrial workers experience long-term sickness absence and how they cope with this situation. The article presents data from in-depth interviews with male industrial workers employed in a Norwegian factory.
Trude Gjernes
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source