Results 81 to 90 of about 1,678,393 (352)

Irrational parenthood cognitions and health-related quality of life among infertile women

International Journal of General Medicine, 2012
Zahra Fardiazar,1 Louiz Amanati,2 Saber Azami31Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; 2Faculty of Medicine, Hacttepe University, Ankara, Turkey; 3Injury Epidemiology and Prevention ...
Fardiazar Z, Amanati L, Azami S
doaj  

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

The impact of biologics on health-related quality of life in patients with inflammatory bowel disease

Clinical and Experimental Gastroenterology, 2009
Lauran Vogelaar1, Adriaan van’t Spijker2, C Janneke van der Woude11Department of Gastroenterology and Hepatology, 2Department of Psychology and Psychotherapy, Erasmus Medical Centre, RotterdamBackground: Inflammatory bowel disease (IBD) is ...
Lauran Vogelaar, Adriaan van’t Spijker, C Janneke van der Woude   +2 more
doaj  

The History of Health Related Quality of Life in 10 1/2 Paragraphs [PDF]

, 1993
Rachel Rosser
openalex   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

The association of drooling and health-related quality of life in children with cerebral palsy

Neuropsychiatric Disease and Treatment, 2012
Shih-Chung Chang,1 Chin-Kai Lin,2 Li-Chen Tung,3 Nai-Yin Chang11Department of Physical Medicine and Rehabilitation, School of Medicine, Chung Shang Medical University Hospital, Taichung, Taiwan; 2Program of Early Intervention, Department of Early ...
Chang SC, Lin CK, Tung LC, Chang NY
doaj  

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Health-related quality of life, anxiety, and depressive symptoms in children with primary immunodeficiencies

Patient Preference and Adherence, 2014
Nina B Kuburovic,1 Srdjan Pasic,2 Gordana Susic,3 Dejan Stevanovic,4 Vladimir Kuburovic,5 Slavisa Zdravkovic,6 Mirjana Janicijevic Petrovic,7 Tatjana Pekmezovic8 1Department of Public Health, Mother and Child Health Care Institute of Serbia, 2Department ...
Kuburovic NB, Pasic S, Susic G, Stevanovic D, Kuburovic V, Zdravkovic S, Janicijevic Petrovic M, Pekmezovic T   +7 more
doaj  

Complete resolution of heartburn symptoms and health‐related quality of life in patients with gastro‐oesophageal reflux disease [PDF]

, 1999
Revicki, Crawley, Zodet, Levine, Joelsson   +4 more
openalex   +1 more source