Results 81 to 90 of about 4,421,151 (391)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

ORAL HEALTH-RELATED QUALITY OF LIFE AND CARIES EXPERIENCE AMONG YOUNG ADULTS

Romanian Journal of Medical and Dental Education, 2023
Young adults represent the age group with the highest ability to understand the need of maintaining good oral health and the highest chance to adopt correct oral hygiene behaviors.
Ștefana Maria Cozma, Livia Bobu, Elena-Raluca Baciu, Gabriela Luminița Gelețu, Roxana-Ionela Vasluianu, Simona Stoleriu, Alice Murariu   +6 more
doaj  

Health-Related Quality of Life in Adrenocortical Carcinoma [PDF]

Cancers, 2019
Insight into the health-related quality of life (HRQoL) impact of adrenocortical carcinoma (ACC) is important. The disease and its treatment options potentially have an impact on HRQoL. For patients with limited survival, HRQoL research is of utmost importance. We will therefore provide an overview of HRQoL studies in patients with ACC.
Harm R Haak, Harm R Haak, Laura A Michon, Rebecca V Steenaard   +3 more
openaire   +3 more sources

A bi-directional relationship between obesity and health-related quality of life : evidence from the longitudinal AusDiab study

, 2012
Objective: To assess the prospective relationship between obesity and health-related quality of life, including a novel assessment of the impact of health-related quality of life on weight gain.Design and setting: Longitudinal, national, population-based
A Hodge, A J Cameron, A Peeters, A Renzaho, AJ Cameron, AJ Cameron, AJ Vickers, CM Alexander, D J Magliano, D W Dunstan, DB Allison, DJ Magliano, DL Zabelina, DW Dunstan, DW Dunstan, E Atlantis, EH Coakley, EL Barr, F Soltoft, FS Luppino, G Hawthorne, H Jia, J E Shaw, JE Ware, JT Fine, K De Vos, K Hesketh, L Barr, LL Yan, M Dalton, M Forhan, M Laaksonen, M Stafford, ME Lean, ML Daviglus, P Bjorntorp, P Bjorntorp, P Serrano-Aguilar, P Z Zimmet, PK Myint, RJ Tapp, RL Kolotkin, S Colagiuri, SL White, WJ Brown, WM Hopman, WS Yancy Jr   +46 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Arterial Hypertension and Health-Related Quality of Life [PDF]

Frontiers in Psychiatry, 2017
To investigate the effect of awareness of arterial hypertension on quality of life in hypertensive patients in Greece.This was a prospective observational study that included 189 aware hypertensive patients on treatment with antihypertensive therapy. Patients were ambulatory men or women ≥18 years old, with diagnosed essential hypertension.
Costas Tsioufis, Konstantinos Kontoangelos, Kyriakos Souliotis, George N. Papadimitriou, P. Sakkas, Petros Nihoyannopoulos, Vasiliki Katsi, Manolis S. Kallistratos, Dimitris Tousoulis   +8 more
openaire   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Associations between health-related quality of life, physical function and fear of falling in older fallers receiving home care [PDF]

, 2018
Falls and injuries in older adults have significant consequences and costs, both personal and to society. Although having a high incidence of falls, high prevalence of fear of falling and a lower quality of life, older adults receiving home care are ...
AF Ambrose, Astrid Bergland, B Rechel, B Thome, B Vellas, C Graf, CJ Jones, Dawn A. Skelton, DM Peters, E Mørk, E von Elm, EC Jørstad, FT Bourgeois, H Hörder, I Araujo de Carvalho, I Vikman, JC Davis, JC Davis, JH Loge, JL Helbostad, K Delbaere, KE Halsaa, KF Schulz, LB Andersson, M Stenhagen, MA Sprangers, Maria Bjerk, N Genet, NT Chang, PC Fletcher, PC Fletcher, RG Cumming, SE Lamb, SH Brown, T Brovold, T Hammar, Therese Brovold, W Lyu, World Health Organization, Y Hellstrom, Y Hellström   +40 more
core   +2 more sources

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Comorbidities, Health-Related Quality of Life, Health-care Utilization in Older Persons with Hemophilia—Hematology Utilization Group Study Part VII (HUGS VII)

Journal of Blood Medicine, 2022
Randall Curtis,1 Marilyn Manco-Johnson,2 Barbara A Konkle,3 Roshni Kulkarni,4 Joanne Wu,5 Judith R Baker,6 Megan Ullman,7 Duc Quang Tran Jr,8 Michael B Nichol5 1Factor VIII Computing, Berkeley, CA, USA; 2Hemophilia and Thrombosis Center, University of ...
Curtis R, Manco-Johnson M, Konkle BA, Kulkarni R, Wu J, Baker JR, Ullman M, Tran DQ Jr, Nichol MB   +8 more
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