Results 231 to 240 of about 8,950,205 (356)

PRO‐LDM: A Conditional Latent Diffusion Model for Protein Sequence Design and Functional Optimization

open access: yesAdvanced Science, EarlyView.
PRO‐LDM is a modular latent diffusion framework that learns hierarchical biological representations to enable efficient and high‐fidelity protein design. PRO‐LDM can design species that resemble natural sequences with enhanced diversity or optimize protein functions.
Sitao Zhang   +15 more
wiley   +1 more source

Mechanical Metamaterial‐Based Structure with Magnetically Controlled Nonreversibility and Nonreciprocity for Programmable Locomotion

open access: yesAdvanced Science, EarlyView.
A magneto‐mechanical metamaterial‐based structure that simultaneously exhibits programmable nonreversibility and nonreciprocity. These cause substantial transitions in static mechanical properties, such as Poisson's ratio and stiffness, leading to stark changes in energy absorption.
Krzysztof K. Dudek   +3 more
wiley   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

open access: yesAdvanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy