Results 161 to 170 of about 25,175,228 (306)

Exploring the Health Effects of Phytoestrogens. [PDF]

Metabolites
Kraus V, Birková A, Majerníková M, Čižmárová B.   +3 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Batchelor Community Health Centre Business Plan 1997/1998

, 1997
Using the Territory Health Services Corporate Plan as a model, the staff of Batchelor Community Health Centre has enthusiastically prepared this Business Plan to serve the future needs of our community.
Batchelor Community Health Centre
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Health effects of air pollution on chronic respiratory diseases. [PDF]

Korean J Intern Med
Jo YS, Song JW.
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Individual-level health effects of living near a gas-fired "Peaker" power plant. [PDF]

J Clim Chang Health
Jung YS, Allen A, Casey J, Henneman L, Shan X, Shirley H, Nadeau K, Duhaime AC.   +7 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

How can the migration of health service professionals be managed so as to reduce any negative effects on supply?

, 2008
28 p.Migration of skilled workers is generally on the increase. In the health sector, physicians, nurses and other health workers have always taken the opportunity to migrate in pursuit of new opportunities and better career prospects.
Buchan, James, Health Evidence Network, European Observatory on Health Systems and Policies, World Health Organization. Regional Office for Europe   +3 more
core