Results 21 to 30 of about 25,175,228 (306)

Genotoxicity assessment of titanium dioxide nanoparticle accumulation of 90 days in the liver of gpt delta transgenic mice

Genes and Environment, 2020
Backgound A variety of in vivo and in vitro studies to assess the genotoxicity of titanium dioxide nanoparticles (TiO2 NPs) have been reported, but the results are inconsistent.
Tetsuya Suzuki, Nobuhiko Miura, Rieko Hojo, Yukie Yanagiba, Megumi Suda, Tatsuya Hasegawa, Muneyuki Miyagawa, Rui-Sheng Wang   +7 more
doaj   +1 more source

Seasonal Variations in PM2.5-induced Oxidative Stress and Up-regulation of Pro-inflammatory Mediators

Aerosol and Air Quality Research, 2020
Inhaling particulate matter with an aerodynamic diameter of ≤ 2.5 µm (PM2.5) has been demonstrated to induce season-dependent adverse health effects. As inflammation and oxidative stress play a critical role in PM2.5-induced health effects, this study ...
Juan Li, Yingying Liu, Zhen An, Wen Li, Xiang Zeng, Huijun Li, Jing Jiang, Jie Song, Weidong Wu   +8 more
doaj   +1 more source

High-fat western diet-consumption alters crystalline silica-induced serum adipokines, inflammatory cytokines and arterial blood flow in the F344 rat

Toxicology Reports, 2022
Adipose tissue (AT) plays a central role in the maintenance of whole-body energy homeostasis through release of adipokines. High-fat Western diet (HFWD)-consumption contributes to obesity, disruption of adipocyte metabolism, chronic systemic inflammation,
Janet A. Thompson, Kristine Krajnak, Richard A. Johnston, Michael L. Kashon, Walter McKinney, Jeffrey S. Fedan   +5 more
doaj   +1 more source

Potential classification of chemical immunologic response based on gene expression profiles

Journal of Immunotoxicology, 2020
Occupational immune diseases are a serious public health burden and are often a result of exposure to low molecular weight (LMW) chemicals. The complete immunological mechanisms driving these responses are not fully understood which has made the ...
Stacey E. Anderson, Rachel Baur, Michael Kashon, Ewa Lukomska, Lisa Weatherly, Hillary L. Shane   +5 more
doaj   +1 more source

Evaluation of the Pulmonary Toxicity of a Fume Generated from a Nickel-, Copper-Based Electrode to be Used as a Substitute in Stainless Steel Welding

Environmental Health Insights, 2014
Epidemiology has indicated a possible increase in lung cancer among stainless steel welders. Chromium (Cr) is a primary component of stainless steel welding fume. There is an initiative to develop alternative welding consumables [nickel (Ni)- and copper (
James M. Antonini, Melissa A. Badding, Terence G. Meighan, Michael Keane, Stephen S. Leonard, Jenny R. Roberts   +5 more
doaj   +1 more source

Mitsui-7, heat-treated, and nitrogen-doped multi-walled carbon nanotubes elicit genotoxicity in human lung epithelial cells

Particle and Fibre Toxicology, 2019
Background The unique physicochemical properties of multi-walled carbon nanotubes (MWCNT) have led to many industrial applications. Due to their low density and small size, MWCNT are easily aerosolized in the workplace making respiratory exposures likely
Katelyn J. Siegrist, Steven H. Reynolds, Dale W. Porter, Robert R. Mercer, Alison K. Bauer, David Lowry, Lorenzo Cena, Todd A. Stueckle, Michael L. Kashon, John Wiley, Jeffrey L. Salisbury, John Mastovich, Kristin Bunker, Mark Sparrow, Jason S. Lupoi, Aleksandr B. Stefaniak, Michael J. Keane, Shuji Tsuruoka, Mauricio Terrones, Michael McCawley, Linda M. Sargent   +20 more
doaj   +1 more source

Systematic review and meta- analysis of selected health effects of long-term exposure to traffic-related air pollution

, 2022
This comprehensive scientific review, available for downloading below, examines the evidence for associations between several adverse health effects and traffic-related air pollution (TRAP). The review, the largest of its type to date, was conducted by a
panel on the health effects of long-term exposure to traffic-rel, H. E. I.
core  

Rat-Tail Models for Studying Hand-Arm Vibration Syndrome: A Comparison between Living and Cadaver Rat Tails

Vibration
Over-exposure of the hand-arm system to intense vibration and force over time may cause degeneration of the vascular, neurological, and musculoskeletal systems in the fingers.
Christopher M. Warren, Xueyan S. Xu, Mark Jackson, Walter G. McKinney, John Z. Wu, Daniel E. Welcome, Stacey Waugh, Phillip Chapman, Erik W. Sinsel, Samantha Service, Kristine Krajnak, Ren G. Dong   +11 more
doaj   +1 more source

Amelioration of PM2.5-induced lung toxicity in rats by nutritional supplementation with fish oil and Vitamin E

Respiratory Research, 2019
Background Exposure to fine particulate matter (PM2.5) has been associated with respiratory morbidity and mortality. Identification of interventional measures that are efficacious against PM2.5-induced toxicity may provide public health benefits.
Juan Li, Hang Li, Haibin Li, Weili Guo, Zhen An, Xiang Zeng, Wen Li, Huijun Li, Jie Song, Weidong Wu   +9 more
doaj   +1 more source

Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis

Journal of Immunotoxicology, 2023
Triclosan is an anti-microbial chemical incorporated into products that are applied to the skin of healthcare workers. Exposure to triclosan has previously been shown to be associated with allergic disease in humans and impact the immune responses in ...
Rachel Baur, Michael Kashon, Ewa Lukomska, Lisa M. Weatherly, Hillary L. Shane, Stacey E. Anderson   +5 more
doaj   +1 more source