Results 101 to 110 of about 582,325 (288)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Practicing medicine in the COVID-19 Pandemic

open access: yesResearch and Humanities in Medical Education, 2021
Frontline clinicians have become society’s line of defence against a raging pandemic. Their stories reflect the uncertainty faced on a daily basis and are witness to their courageous acts first-hand.
Mariella Scerri, Victor E Grech
doaj  

The humanities university chair response to health services dehumanized [PDF]

open access: yes, 2014
Los servicios de salud en Colombia recientemente se están caracterizando por una atención médica deshumanizante a causa de diferentes factores, entre ellos la relación médico/paciente, derivándose en la calidad de la atención, aunque lo anterior no es ...
Castro Jerez, Jairo
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Health Humanities in Medicina: The Auxiliary Stance. [PDF]

open access: yesMedicina (Kaunas), 2022
Dammann O, Mežinska S, Gefenas E.
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An Overview of the Nonprofit and Charitable Sector [PDF]

open access: yes, 2009
[Excerpt] A number of policy issues have direct or indirect consequences for the nonprofit and charitable sector, including the establishment of a social innovation initiative, changes in the tax treatment of charitable donations, responses to the ...
Gravelle, Jane G, Sherlock, Molly F
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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