Results 91 to 100 of about 1,566,265 (296)

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

An Introduction to Health Information Exchange: a Review Article

open access: yesمدیریت اطلاعات سلامت, 2015
Instant access to individuals, health information is influential for the health promotion throughout the community in both personal and public domains. Patients’ lives endanger due to lack of timely access to their own health information and subsequently
Tahereh Naseri Boori Abadi
doaj  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Doctors' Orders or Patients' Preferences? Examining the Role of Physicians in Patients' Privacy Decisions on Health Information Exchange Platforms

open access: yesJournal of the AIS, 2019
Health information exchange (HIE) platforms could increase the efficiency of health care services by enabling providers to instantly access the medical records of their patients.
Niam Yaraghi, R. Gopal, R. Ramesh
semanticscholar   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Large-scale implementation and adoption of the Finnish national Kanta services in 2010–2017: a prospective, longitudinal, indicator-based study

open access: yesFinnish Journal of eHealth and eWelfare, 2018
In Finland, implementation and adoption of the national Kanta services’ second phase services were carried out step-by-step from May 2010 till December 2017. The Kanta services currently include integrated, interoperable health information from EMR, EHR,
Vesa Jormanainen
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Standard compliant communication of motion data in a telemonitoring system

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie, 2015
Interoperability is regarded as one of the key factors for the high acceptance of a telemonitoring system. In a general telemonitoring scenario for motion tracking, data recorded by inertial sensors should be sent from the patient's home to a central ...
Piro, Neltje Emma   +3 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

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