Results 91 to 100 of about 2,047,765 (296)

Quality and Safety Aspects of Infant Nutrition [PDF]

, 2012
Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition.
Agostoni C, Agostoni C, Agostoni C, Aris B, Berthold Koletzko, Bier DM, Birlouez-Aragon I, Bonerba E, Cahill SM, Chang H, Dabeka R, Davanzo R, Day JB, Dewey KG, Domellof M, El-Tras WF, Erkekoglu P, Fattal-Valevski A, Fattal-Valevski A, Fattal-Valevski A, Fewtrell MS, Fewtrell MS, Flores JP, Friedman M, Gossner CM, Guzel A, Hamrin P, Hernell O, Hilbig A, Hirvonen T, Jongenburger I, Kaleita TA, Khlangwiset P, Kim SA, Koletzko B, Koletzko B, Koletzko B, Kornreich L, Kvist LJ, Lanska DJ, Lönnerdal B, Malloy MH, Margaret Ashwell, Miled RB, Mitkus RJ, Newberry RE, Norberg S, Oluwafemi F, Panfeng S, Pavesi Arisseto A, Raanan Shamir, Raecker T, Rebhan B, Reij MW, Ruiz E, Santillana MI, Schoder D, Shamir R, Silver LB, Simoneau C, Simoneau C, Snijder CA, Snijder CA, Szajewska H, Szajewska H, Turck D, Weistaub G, Welch RW, Whyatt RM, Willoughby A, Yen TH, Zlotkin S   +71 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Authentication of Patients and Participants in Health Information Exchange and Consent for Medical Research: A Key Step for Privacy Protection, Respect for Autonomy, and Trustworthiness

Frontiers in Genetics, 2018
Genome and other data are already being used in areas including cancer and rare diseases. Data-sharing and secondary uses are likely to become much broader and far more extensive; thus, obtaining proper consent for these new uses of data is an important ...
Atsushi Kogetsu, Soichi Ogishima, Kazuto Kato   +2 more
doaj   +1 more source

Personal Privacy and Common Goods: A Framework for Balancing Under the National Health Information Privacy Rule [PDF]

, 2002
In this Article, we discuss how these principles for balancing apply in a number of important contexts where individually identifiable health data are shared. In Part I, we analyze the modern view favoring autonomy and privacy.
Gostin, Lawrence O., Hodge, James G., Jr.   +1 more
core   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

The Northwest Public Health Information Exchange’s Accomplishments in Connecting a Health Information Exchange with Public Health

Online Journal of Public Health Informatics, 2010
In 2007 the Centers for Disease Control and Prevention (CDC) issued a Request for Proposal for the "Situational Awareness through Health Information Exchange" project. The Situational Awareness project's goals are to connect public health with health information exchanges (HIEs) to improve public health's real-time understanding of communities ...
Dobbs, D, Trebatoski, M, Revere, D
openaire   +3 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

An Introduction to Health Information Exchange: a Review Article

مدیریت اطلاعات سلامت, 2015
Instant access to individuals, health information is influential for the health promotion throughout the community in both personal and public domains. Patients’ lives endanger due to lack of timely access to their own health information and subsequently
Tahereh Naseri Boori Abadi
doaj