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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Health Care Information Technology: Securing the Electronic Health Record with Biometric Technology [PDF]
The principal focus of this paper is to examine the integration of biometric technology into healthcare’s information technology systems. Biometric technology, a rapidly evolving mechanism, analyzes specific anatomical and physiological features of an ...
Iacona, Alyssa
core +1 more source
Healthcare disparities and models for change. [PDF]
With Healthy People 2010 making the goal of eliminating health disparities a national priority, policymakers, researchers, medical centers, managed care organizations (MCOs), and advocacy organizations have been called on to move beyond the historic ...
Baquet, Claudia R +2 more
core +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
How to Evaluate Health Information Systems: Evaluation stages [PDF]
The most important goal of health systems is improvement of quality, effectiveness and efficiency of health services. To achieve this goal, health care organizations should establish a proper structure for evaluating health information systems.
Farahnaz Sadoughi, Farzaneh Aminpour
doaj
Factors Affecting Outsourcing for Information Technology Services in Rural Hospitals: Theory and Evidence [PDF]
As health information technology becomes more prevalent for most healthcare facilities, hospitals across the nation are choosing between performing this service in-house and outsourcing to a technology firm in the health industry.
Barnes, James N. +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Challenges and Opportunities of Telemedicine: A Narrative Review Study
Immediate access to special clinical services remotely has an important role in transferring information, informing clinical diagnosis, and distance learning.
Shiva Mafi-Moradi +2 more
doaj +1 more source
mHealth in China and the United States: How Mobile Technology is Transforming Healthcare in the World's Two Largest Economies [PDF]
In this paper, we explore ways mobile technology can help with these difficulties. Specifically, we look at avenues through which mobile devices boost productivity, aid communications, and help providers improve affordability, access, and treatment ...
Darrell West +11 more
core
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source

