Results 91 to 100 of about 706,349 (318)
The Relationships between Social Determinants of Health and Health-related Quality of Life among the Community-dwelling Elderly [PDF]
, 2014 Purpose: The purpose of this study was to examine the social determinants of health (SDH) associated with health-related quality of life (HQOL) among the community-dwelling elderly, based on the conceptual framework of the Commission on Social ...
김정희 +3 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The Awareness of Elderly about Osteoporosis: What about Our Elderly?
, 2015 Objective: Osteoporosis (OP) and bone fractures that can result in pain, functional impairment and death are important public health problems for the elderly.
Şule Şahin Onat +5 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Revista Brasileira de Geriatria e GerontologiaO objetivo deste artigo foi identificar, com base na literatura, como a saúde do idoso e o envelhecimento têm sido abordados na formação universitária dos profissionais de saúde e o que vem sendo considerado relevante nesta temática.
Claudia Reinoso Araujo de Carvalho +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Maǧallaẗ Al-Turāṯ wa Al-TaṣmīmMany older people lose their ability to live independently, due to limited movement, chronic pain, weakness, or other psychological and physical problems, all of these factors can lead to loneliness and psychological distress to them, so they need a form
Dr. Mona Sayed Othman Badr Othman
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Public Policy and Health Care Choices of the Elderly: Evidence from the Medicare Buy-In Program [PDF]
This study provides evidence on the economic decisions of senior citizens with respect to the largest means-tested program in the United States: the Medicaid program. Virtually all senior citizens have health insurance coverage through Medicare, but poor
A. S. Yelowitz
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