Results 71 to 80 of about 706,349 (318)

O olhar dos conselheiros de saúde da Região Metropolitana de São Paulo sobre serviços de saúde para idosos: 'Quem cuidará de nós em 2030?'

Saúde em Debate
O estudo foi desenvolvido por meio de um recorte da pesquisa: 'Quem cuidará de nós em 2030?'. Sob a ótica dos conselheiros de saúde buscou-se compreender a percepção sobre os serviços oferecidos hoje e os que seriam necessários em 2030 para os idosos. Ao
Ana Paula Leal Loureiro da Silva, Otávio Toledo Nóbrega, Beltrina Côrte   +2 more
doaj   +1 more source

Long-stay institutions for the elderly: physical-structural and organizational aspects

Escola Anna Nery, 2017
Objective: To characterize long-stay institutions for the elderly in respect to physical-structural and organizational aspects. Method: This descriptive, cross-sectional, quantitative research was carried out in four long-stay institutions for the ...
Manuela Bastos Alves, Maria do Rosário de Menezes, Ridalva Dias Martins Felzemburg, Valdenir Almeida da Silva, Juliana Bezerra do Amaral   +4 more
doaj   +1 more source

Patients’ experiences with fluctuations in persistent physical symptoms: a qualitative study

BMJ Open, 2020
Objectives To explore patients’ experiences with fluctuations in persistent physical symptoms (PPS) and to understand which factors—from their viewpoint—play a role in these fluctuations.Design Qualitative study using semistructured interviews and ...
Johannes C van der Wouden, Hieke Barends, Ella Walstock, Femke Botman, Anja de Kruif, Nikki Claassen, Tim olde Hartman, Joost Dekker, Henriette van der Horst   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Brazilian Consensus On Frailty In Older People: Concepts, Epidemiology And Evaluation Instruments [PDF]

Geriatrics, Gerontology and Aging
The aim of the present study was to describe the conceptual and operational definitions of the frailty syndrome recommended by the Brazilian Consensus on Frailty in Older People.
Roberto Alves Lourenço, Virgílio Garcia Moreira, Renato Gorga Bandeira de Mello, Itamar de Souza Santos, Sumika Mori Lin, Ana Lúcia Fiebrantz Pinto, Lygia Paccini Lustosa, Yeda Aparecida de Oliveira Duarte, Juliana Alcântara Ribeiro, Clarice Câmara Correia, Henrique Novaes Mansur, Euler Ribeiro, Roberta Rigo Dalla Corte, Eduardo Ferriolli, Carlos André Uehara, Ana Maeda, Tamara Petroni, Terezinha Silva Lima, Sergio Falcão Durão, Ivan Aprahamian, Carla Maria Avesani, Wilson Jacob Filho   +21 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Declines in Activities in Daily Living of Older Adults with Sarcopenia Were Associated with Gait Speed

Medicina
Background and Objectives: Early assessment interventions are recommended for older adults with sarcopenia. Gait speed in older adults considerably decreases activities of daily living (ADL).
Ryo Sato, Yohei Sawaya, Tamaki Hirose, Takahiro Shiba, Lu Yin, Shuntaro Tsuji, Masahiro Ishizaka, Tomohiko Urano   +7 more
doaj   +1 more source

Health education as a strategy for the promotion of the health of the elderly: an integrative review

Revista Brasileira de Geriatria e Gerontologia, 2019
Objective: To identify the key issues and health education strategies for the health promotion for the elderly. Method: An integrative literature review was conducted during the months of March and April 2018, by means of the Virtual Health Library, in ...
Cícera Amanda Mota Seabra, Samyra Paula Lustoza Xavier, Yana Paula Coêlho Correia Sampaio, Mirna Fontenele de Oliveira, Glauberto da Silva Quirino, Maria de Fátima Antero Sousa Machado   +5 more
doaj   +2 more sources