Results 141 to 150 of about 1,128,412 (358)

The legal path for priority setting in Chile: a critical analysis to improve health planning and stewardship

open access: yesFrontiers in Public Health
Health systems have committed their path to universal health coverage using health planning to accomplish their goals of efficiency, equity and sustainability.
Manuel Antonio Espinoza   +5 more
doaj   +1 more source

National cancer programme work plan 2014/15 [PDF]

open access: yes
The National Cancer Programme Work Plan 2014/15 covers national, regional and local priority activities for cancer. Overview The National Cancer Programme: brings together the work of district health boards, regional cancer networks and the Ministry

core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Health and nutrition: emerging and reemerging issues in developing countries [PDF]

open access: yes
CONTENTS: Brief 1. Overview / Rafael Flores Brief 2. The Global Burden of Disease / Alan D. Lopez Brief 3. HIV/AIDS / Anthony Barnett and Gabriel Rugalema Brief 4. Malaria / Andrea Egan Brief 5. Tuberculosis / Ariel Pablos-Mendez Brief 6.
Flores, Rafael, ed.   +1 more
core  

Developing our evidence base (information document) [PDF]

open access: yes, 2009
"Purpose: “To provide high quality ,timely evidence that informs and challenges DCELLS strategies , policies and programmes”. This document outlines DCELLS' current and future analytical priorities.

core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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