Results 171 to 180 of about 220,169 (313)

"It's not just HIV anymore": A qualitative exploration of health, research, community and mental health priorities of long-term survivors of HIV in the United States. [PDF]

AIDS Care
Ahmed A, Taylor J, Lai JC, Lau R, Diunugala SD, Louella M, Brown B, Nguyen AL, Karris M, Dee L, Berry J, Dubé K.   +11 more
europepmc   +1 more source

Acceptability and use of an online health priorities self-identification tool for older adults: A qualitative investigation. [PDF]

PEC Innov, 2023
Mroz EL, Hernandez-Bigos K, Esterson J, Kiwak E, Naik A, Tinetti ME.   +5 more
europepmc   +1 more source

Availability and affordability of priority life-saving medicines for under-five children in health facilities of Tigray region, northern Ethiopia [PDF]

, 2018
Solomon Abrha, Ebisa Tadesse, Tesfay Mehari Atey, Fantahun Molla, Wondim Melkam, Birhanetensay Masresha, Solomon Gashaw, Abrham Wondimu   +7 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Plastic Surgical Outreach to Low- and Middle-income Countries and Global Health Priorities: An Analysis of 96 Nongovernmental Organizations. [PDF]

Plast Reconstr Surg Glob Open, 2023
Yan A, Castellanos SL, Chao AH.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Balancing public health priorities and inclusivity in medical education: a clarification on curriculum revisions. [PDF]

Lancet Reg Health Southeast Asia
Beg MJ, Chaitanya Reddy BS, Singh Sethi MI.   +2 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Global kidney health priorities-perspectives from the ISN-GKHA. [PDF]

Nephrol Dial Transplant
Okpechi IG, Luyckx VA, Tungsanga S, Ghimire A, Jha V, Johnson DW, Bello AK.   +6 more
europepmc   +1 more source