An electronic family health history tool to identify and manage patients at increased risk for colorectal cancer: protocol for a randomized controlled trial. [PDF]
, 2019 BackgroundColorectal cancer is the fourth most commonly diagnosed cancer in the United States. Approximately 3-10% of the population has an increased risk for colorectal cancer due to family history and warrants more frequent or intensive screening. Yet,
Coffman, Cynthia J +15 more
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
HOURS OF GAMING OR NON-ACADEMIC COMPUTER USE, SUBSTANCE USE, MENTAL HEALTH STATUS AND SCHOOL PERFORMANCE AMONG TEXAS ADOLESCENCE: FINDINGS FROM THE 2017 YRBS IN TEXAS [PDF]
, 2018 Online gaming activities among adolescents and adults has increased exponentially in the last decade, and mental health issues associated with excessive gaming have drawn attention from health care professionals worldwide (Griffith, 2016).
Gao, Shanxiazi
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The Development of the Irish Private Health Insurance Market and Evidence of Selection Effects Therein [PDF]
This paper tracks the development of the Irish private health insurance market, both in terms of its legislative background and the development of competition. Literature on adverse selection and risk selection is then reviewed.
Brian Turner, Edward Shinnick
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Attitudes of Risk Management Professionals Toward Disclosure of Medical Mistakes [PDF]
, 2001 The author reports on health care organization risk managers\u27 attitudes toward disclosure of medical ...
Ruroede, Kathleen
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Current and future temperature suitability for autochthonous transmission of malaria in Canada
International Journal of Health GeographicsBackground Malaria continues to be one of the most significant infectious diseases in terms of morbidity and mortality. In many parts of North America, including parts of southern Canada, competent malaria vectors Anopheles quadrimaculatus and Anopheles ...
Kevin Siebels +4 more
doaj +1 more source
Uncertainty in epidemiology and health risk assessment [PDF]
, 2009 D J, Briggs, K, Lee, Sabel, Clive E
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