Results 91 to 100 of about 4,533,217 (309)

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis

Molecular Cancer, 2020
Background The poor prognosis of esophageal squamous cell carcinoma (ESCC) highlights the need for novel strategies against this disease. Our previous study suggested the involvement of CCL2 and tumor associated macrophages (TAMs) in esophageal ...
Hui Yang, Qiannan Zhang, Miao Xu, Lei Wang, Xuewei Chen, Yongquan Feng, Yongning Li, Xin Zhang, Wenming Cui, Xudong Jia   +9 more
doaj   +1 more source

Developing an Actuarial Risk Assessment to Inform the Decisions Made by Adult Protective Service Workers [PDF]

, 2010
In 2008, the New Hampshire Department of Health and Human Services Bureau of Elderly and Adult Services (BEAS) and the National Council on Crime and Delinquency (NCCD), with funding provided by the National Institute of Justice (NIJ), collaborated to ...
Andrea Bogie, Dennis Wagner, Kathy Park, Kristen Johnson   +3 more
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Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

The prevalence of nutrition risk and associated risk factors among older adults recently admitted to age-related residential care within the Waitemata District Health Board region : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition and Dietetics at Massey University, Auckland, New Zealand [PDF]

, 2017
Background: New Zealand has a rapidly growing ageing population, aligned with the ageing population trend occurring globally. Older adults account for a significant proportion of the government health care expenditure, primarily due to higher needs for
Hettige, Dushanka
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Assessment of Postural Load during Melon Cultivation in Mediterranean Greenhouses [PDF]

, 2018
Health and safety at work directly influence the development of sustainable agriculture. In the agricultural sector, many farm workers suffer musculoskeletal disorders caused by forced posture. The objective of this research is to assess working postures
Callejón Ferre, Ángel Jesús, Gómez Galán, Marta, Pérez Alonso, José, Sánchez-Hermosilla López, Julián   +3 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hepatitis E virus: a foodborne pathogen of concern in China

One Health Advances
Hepatitis E, caused by hepatitis E virus (HEV), is a major global health concern with an estimated 20 million infections and 3.3 million symptomatic cases annually, resulting in approximately 44,000 deaths.
Jiahui Wang, Suzie Coughlan, Fengqin Li, Gabriel Gonzalez, Séamus Fanning, Nan Li, Yinping Dong, Tao Jiang   +7 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Influenza Vaccinations Among Pregnant Women in Georgia: The Provider Role [PDF]

, 2005
Georgia's data from the Pregnancy Risk Assessment Monitoring System (PRAMS) reveal several reasons why women do not receive influenza vaccinations during pregnancy.

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