Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Lack of in vivo mutagenicity of carbendazim in the liver and glandular stomach of MutaMice
Background Carbendazim (methyl 2-benzimidazolecarbamate, CASRN: 10605-21-7) exhibits spindle poisoning effects and is widely used as a fungicide. With respect to genotoxicity, carbendazim is deemed to be non-mutagenic in vitro, but it causes indicative ...
Takako Iso +9 more
doaj +1 more source
Health Effects and Risk Assessment
Detailed risk assessments for methylmercury have been recently published by national and international bodies (e.g., the (U.S.) National Research Council (NRC, 2000), the U.S.
Grandjean, Philippe +4 more
openaire +3 more sources
Bioaccessibility and human health risk : chromium in Glasgow [PDF]
The assessment of risk to human health from contaminated land is based on a comparison of predicted human exposure to a contaminant with a Health Criteria Value (HCV) that represents an exposure below which there is thought to be little or no risk to ...
Bewley, RJ.F. +5 more
core
Worldwide Exposures to Cardiovascular Risk Factors and Associated Health Effects: Current Knowledge and Data Gaps. [PDF]
Information on exposure to, and health effects of, cardiovascular disease (CVD) risk factors is needed to develop effective strategies to prevent CVD events and deaths.
Elliott, P +3 more
core +1 more source
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Natural Occurrence of Alternaria Toxins in the 2015 Wheat from Anhui Province, China
The exposure to Alternaria toxins from grain and grain-based products has been reported to be related to human esophageal cancer in China. In this study, a total of 370 freshly harvested wheat kernel samples collected from Anhui province of China in 2015
Wenjing Xu +3 more
doaj +1 more source
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
Establishment and application of health risk ranking model for heavy metals in aquatic products
Objective To develop a scientific and rapid risk ranking model that is suitable for the analysis of data from food chemicals surveillance system. Methods Based on the principles of food safety risk assessment, a series of index were developed for the ...
Ning MA +8 more
doaj +1 more source
Use of the HCR-20 for violence risk assessment:views of clinicians working in a secure inpatient mental health setting [PDF]
Purpose: To explore how raters combine constituent components of HCR-20 risk assessment for inpatient aggression, and how relevant they rate the tool for different diagnostic and demographic groups.Design/methodology/approach: A cross-sectional survey ...
Dickens, Geoffrey L., O'Shea, Laura E.
core +2 more sources

