Results 101 to 110 of about 4,483,049 (377)

Reusable Services from the neuGRID Project for Grid-Based Health Applications [PDF]

Studies in Health Technology & Informatics Vol 147, pp 283-288 ISBN 978-1-60750-027-8 IOS Press. 2009, 2012
By abstracting Grid middleware specific considerations from clinical research applications, re-usable services should be developed that will provide generic functionality aimed specifically at medical applications. In the scope of the neuGRID project, generic services are being designed and developed which will be applied to satisfy the requirements of
arxiv  

Changing the paradigm : reflections on experiences in workshops to reduce stigma and discrimination in mental health services : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Philosophy at Massey University [PDF]

, 2001
One of the key objectives of the national Like Minds, Like Mine project against stigma and discrimination associated with mental illness is to work with the mental health sector to change attitudes and behaviour through education and policy development ...
Gerzon, Ruth
core  

Exposing the impact of Citizens Advice Bureau services on health: a realist evaluation protocol [PDF]

, 2016
Introduction Welfare advice services can be used to address health inequalities, for example, through Citizens Advice Bureau (CAB). Recent reviews highlight evidence for the impact of advice services in improving people's financial position and ...
Carr, Susan, Dalkin, Sonia, Forster, Natalie, Hodgson, Philip, Lhussier, Monique   +4 more
core   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Regularization and Hierarchical Prior Distributions for Adjustment with Health Care Claims Data: Rethinking Comorbidity Scores [PDF]

arXiv, 2017
Health care claims data refer to information generated from interactions within health systems. They have been used in health services research for decades to assess effectiveness of interventions, determine the quality of medical care, predict disease prognosis, and monitor population health. While claims data are relatively cheap and ubiquitous, they
arxiv  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Using SOA with Web Services for effective Integration of Hospital Information Systems via an Enterprise Service Bus [PDF]

International Journal of Research in Engineering & Advanced Technology (IJREAT).pp: 1-6.1.2.(2013), 2013
Hospitals are distributed across geographical areas and it is important for all hospitals to share information as well as integrate their systems for effective researching and health delivery. Health personals and institutions in need of information from hospitals with respect to geographical areas can easily do researches on patients, treatments ...
arxiv  

Effects of Perceived Stigma from College Friends on Students Utilizing Mental Health Services [PDF]

, 2016
This paper explores the relationship between perceived stigma from friends and the use of mental health services. By reviewing six peer-reviewed articles it was hypothesized that there would be a negative correlation between the number of Virginia ...
Okai, Shammah N
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Failure to Rescue as an Outcome Metric for Pediatric and Congenital Cardiac Catheterization Laboratory Programs: Analysis of Data From the IMPACT Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Risk‐adjusted adverse event (AE) rates have been used to measure the quality of pediatric and congenital cardiac catheterization laboratories. In other settings, failure to rescue (FTR) has demonstrated utility as a quality metric. Methods and
Michael L. O'Byrne, Kevin F. Kennedy, Natalie Jayaram, Lisa J. Bergersen, Matthew J. Gillespie, Yoav Dori, Jeffrey H. Silber, Steven M. Kawut, Jonathan J. Rome, Andrew C Glatz   +9 more
doaj   +1 more source