Results 51 to 60 of about 4,483,049 (377)

Enhancing Health Care Accessibility and Equity Through a Geoprocessing Toolbox for Spatial Accessibility Analysis: Development and Case Study [PDF]

open access: yesJMIR Form Res JMIR Formative Research. 2024 Feb 21:8:e51727
Access to health care services is a critical determinant of population health and well-being. Measuring spatial accessibility to health services is essential for understanding health care distribution and addressing potential inequities. In this study, we developed a geoprocessing toolbox including Python script tools for the ArcGIS Pro environment to ...
arxiv   +1 more source

The Public Health PBRN Program: A Summative Report [PDF]

open access: yes, 2013
This program seeks to expand the volume and quality of evidence on how best to organize, finance, and deliver public health services by: (1) helping to organize and develop practice-based research networks (PBRNs) comprised of public health agencies and ...
Center for Public Health Systems and Services Research
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Blockchain protocols in clinical trials: Transparency and traceability of consent [version 3; referees: 1 approved, 2 approved with reservations, 1 not approved]

open access: yesF1000Research, 2017
Clinical trial consent for protocols and their revisions should be transparent for patients and traceable for stakeholders. Our goal is to implement a process allowing the collection of patients’ informed consent, which is bound to protocol revisions ...
Mehdi Benchoufi   +2 more
doaj   +1 more source

Understanding and Mitigating Mental Health Misinformation on Video Sharing Platforms [PDF]

open access: yesarXiv, 2023
Despite the ever-strong demand for mental health care globally, access to traditional mental health services remains severely limited expensive, and stifled by stigma and systemic barriers. Thus, over the last few years, young people are increasingly turning to content on video-sharing platforms (VSPs) like TikTok and YouTube to help them navigate ...
arxiv  

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

A promising approach to scale up health care improvements in low-and middle-income countries: the Wave-Sequence Spread Approach and the concept of the Slice of a System [v1; ref status: indexed, http://f1000r.es/37o]

open access: yesF1000Research, 2014
There are several examples of successes in improving health care. However, many of these tend to remain limited to the sites they were originally developed in.
M. Rashad Massoud, Nana Mensah-Abrampah
doaj   +1 more source

Transition of care from child to adult mental health services : the great divide [PDF]

open access: yes, 2009
Purpose of review: Adolescents with mental health problems often require transition of care from child and adolescent to adult mental health services.
Singh, Swaran P.
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Improving educational environment in medical colleges through transactional analysis practice of teachers [v1; ref status: indexed, http://f1000r.es/R3KKeG]

open access: yesF1000Research, 2012
Context: A FAIMER (Foundation for Advancement in International Medical Education and Research) fellow organized a comprehensive faculty development program to improve faculty awareness resulting in changed teaching practices and better teacher student ...
Marina Rajan, Thomas Chacko
doaj   +1 more source

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