Results 101 to 110 of about 6,736,762 (309)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Electronical Health Record's Systems. Interoperability [PDF]
, 2009 Understanding the importance that the electronic medical health records system has, with its various structural types and grades, has led to the elaboration of a series of standards and quality control methods, meant to control its functioning.
Apostol, Miss Angela Simona +2 more
core
Editorial: Lessons learned from the Rehabilitation International World Congress—moving societies
Frontiers in Rehabilitation Sciences, 2022 Reuben Escorpizo
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Diabetes, Metabolic Syndrome and ObesityYan Xue,1 Menghuan Song,1,2 Honho Yu,3 Xianwen Chen,1 Carolina Oi Lam Ung,1,2,4 Hao Hu1,2,4 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, People’s Republic of China ...
Xue Y +5 more
doaj
Changes in the public health infrastructure in Poland in the context of an aging population
Journal of Education, Health and Sport, 2018 The problem of an aging society, particularly the health situation of a group of older people is a challenge for health care for the coming years. Poland among other EU member states has one of the lowest (1) share of the population aged 65 years and ...
Monika Pajewska +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
How health systems in sub-Saharan Africa can benefit from tuberculosis and other infectious disease programmes. [PDF]
, 2009 Weak and dysfunctional health systems in low-income countries, particularly in sub-Saharan Africa, are recognised as major obstacles to attaining the health-related Millennium Development Goals by 2015.
Enarson, D A +4 more
core +1 more source