Results 71 to 80 of about 5,541,202 (305)

Increasing the Capacity of Primary Care Through Enabling Technology. [PDF]

, 2017
Primary care is the foundation of effective and high-quality health care. The role of primary care clinicians has expanded to encompass coordination of care across multiple providers and management of more patients with complex conditions.
Nesbitt, Thomas S, Young, Heather M
core   +1 more source

In-community vision testing device development using a Kaupapa Māori framework

Kōtuitui
We report on a 2019 project in which we ran in-community testing of a novel device for measuring visual acuity (the measure of performance obtained by an eye chart).
Jason Turuwhenua, Joanna Black, Misty Edmonds   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Explaining the Health Information Technology Paradox [PDF]

, 2014
Excerpt] The substantial gap between the promise inherent in upgrading information systems in health care and the documented reality has baffled health care scholars. Why is a technology so clearly capable of creating efficiencies, increasing safety, and
Avgar, Ariel C, Litwin, Adam Seth
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Opening the Black Box: Explaining the Process of Basing a Health Recommender System on the I-Change Behavioral Change Model [PDF]

, 2019
Recommender systems are gaining traction in healthcare because they can tailor recommendations based on users' feedback concerning their appreciation of previous health-related messages. However, recommender systems are often not grounded in behavioral
Amaya Rodríguez, Claudio Antonio, Bamidis, Panagiotis D., Civit Balcells, Antón, Hors Fraile, Santiago, Li, Yuchuan, Luna Perejón, Francisco, Malwade, Shwetambara, Schneider, Francine, Syed-Abdul, Shabbir, Vries, Hein de   +9 more
core   +1 more source

Quantifying Induced Nystagmus Using a Smartphone Eye Tracking Application (EyePhone)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background There are ≈5 million annual dizziness visits to US emergency departments, of which vestibular strokes account for over 250 000. The head impulse, nystagmus, and test of skew eye examination can accurately distinguish vestibular strokes from ...
Pouya B. Bastani, Hector Rieiro, Shervin Badihian, Jorge Otero‐Millan, Nathan Farrell, Max Parker, David Newman‐Toker, Yuxin Zhu, Ali Saber Tehrani   +8 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Comparison of Nurses’ Digital Literacy Levels: A Study in Digital and Non-Digital Hospitals

Forbes Tıp Dergisi
Objective: The aim of this study is to compare the digital literacy levels of nurses working in digital and non-digital hospitals and to examine the effect of demographic and professional variables on their digital competence.
Mustafa ORHAN, Süleyman MERTOĞLU
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source