Results 71 to 80 of about 2,126,506 (298)
Promoting safety through well-being: an experience in healthcare
Practitioners’ well-being and clinical risk management are two interrelated concepts in healthcare. Patient safety, workers’ safety and practitioners well-being have often been managed and measured with different methods, even though they are tightly ...
Andreina Bruno, Fabrizio Bracco
doaj +1 more source
Healthcare Access vs. Quality Healthcare: Rethinking Healthcare Risks
ObjectivesThis narrative literature review examines the global burden of mortalities due to poor quality care compared to mortalities resulting from lack of access to healthcare, focusing on the period from 2015 to 2024.MethodsData was extracted from electronic databases such as PubMed, Google Scholar, Scopus, Ebscohost, and WHO. Relevant statistics on
openaire +3 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Healthcare Worker Reported Dead from Creutzfeldt- Jakob Disease [PDF]
Gina Pugliese
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Balancing Healthcare and Economy Amidst the COVID-19 Pandemic: An Indian Experience
Ruby Dhar,1,* Babban Jee,2,* Subhradip Karmakar1 1Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India; 2Department of Health Research, Ministry of Health and Family Welfare, Government of India, New Delhi, India*These ...
Dhar R, Jee B, Karmakar S
doaj
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun+5 more
wiley +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Prevention and intervention strategies to check increasing violence against healthcare facilities and healthcare professionals [PDF]
Shaukat Ali Jawaid
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This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source