Results 21 to 30 of about 429,551 (311)
Scientific Reports, 2021 Here, we investigated the genetics of weighted functional brain network graph theory measures from 18,445 participants of the UK Biobank (44–80 years). The eighteen measures studied showed low heritability (mean h2 SNP = 0.12) and were highly genetically
Heidi Foo +6 more
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Nitric oxide-induced ribosome collision activates ribosomal surveillance mechanisms
Cell Death and Disease, 2023 Impairment of protein translation can cause stalling and collision of ribosomes and is a signal for the activation of ribosomal surveillance and rescue pathways.
Laura Ryder +8 more
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Healthy Aging as Disease? [PDF]
Frontiers in Aging Neuroscience, 2011 In the scientific and popular literature recently there has been a widespread call for classifying normal aging as a disease, a condition that can be “manipulated, treated, and delayed” (Gems, 2010; Kelland, 2010). The main argument given by supporters of this suggestion is that grant-awarding bodies would be more likely to fund research into how, when,
openaire +3 more sources
Housing Poverty and Healthy Aging in China: Evidence from the China Health and Retirement Longitudinal Study [PDF]
, 2021 Background: Although prior research on the housing–health linkage suggested that those with poor housing conditions are more likely to report poor health, it is dominated by Western studies and offers little evidence on the housing–health relation in ...
Lanlin Ding +3 more
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Skeletal endocrinology: where evolutionary advantage meets disease
Bone Research, 2021 The regulation of whole-body homeostasis by the skeleton is mediated by its capacity to secrete endocrine signaling molecules. Although bone-derived hormones confer several adaptive benefits, their physiological functions also involve trade-offs, thus ...
Nikolai Jaschke +4 more
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Endocrine Connections, 2023 The link between obesity and low bone strength has become a significant medical concern. The canonical Wnt signaling pathway is a key regulator of mesenchymal stem cell differentiation into either osteoblasts or adipocytes with active Wnt signaling ...
Souad Daamouch +3 more
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Protein and healthy aging [PDF]
The American Journal of Clinical Nutrition, 2015 Our understanding of the potential benefits and challenges of optimizing dietary protein intake in older adults continues to evolve. An overarching hypothesis generated during Protein Summit 2.0 was that consuming an adequate amount of high-quality protein at each meal, in combination with physical activity, may delay the onset of sarcopenia, slow its ...
Paddon-Jones, Douglas +6 more
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The time course of selected outcome measures in healthy women aged 65-74 years when varying exercise frequency and duration of an exercise walking programme [PDF]
, 2014 Background: We aimed to determine the time course of resting and exercise heart rates (HR); blood pressure (BP), changes in peak VO2, time to exhaustion (TTE) and gas exchange threshold (Tge) at a constant weekly exercise time [120 mins] with ...
Gass, Gregory +8 more
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Healthy ageing: ageing safely [PDF]
European Heart Journal Supplements, 2001 The population of the developed world is steadily ageing. In the European Union, approximately 22% of persons are over 60 years of age and this is projected to increase to more than 27% by the year 2020. This has major implications for health care resources and the productive workforce. Ageing is accompanied by a decline in the physiological reserve of
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Psychological Wellbeing and Healthy Aging: Focus on Telomeres [PDF]
, 2019 Stress and depression are known to modulate the aging process, and might also affect telomere biology. In fact, exposure to some biochemical pathways involved in stress-related depression may contribute to an ‘‘accelerated aging„ ...
Mariangela Boccardi, Virginia Boccardi
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