Results 21 to 30 of about 403,438 (266)
Endocrine Connections, 2023 The link between obesity and low bone strength has become a significant medical concern. The canonical Wnt signaling pathway is a key regulator of mesenchymal stem cell differentiation into either osteoblasts or adipocytes with active Wnt signaling ...
Souad Daamouch +3 more
doaj +1 more source
Stable Isotope-Labeled Lipidomics to Unravel the Heterogeneous Development Lipotoxicity
Molecules, 2018 Non-alcoholic fatty liver disease (NAFLD) as a global health problem has clinical manifestations ranging from simple non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), cirrhosis, and cancer.
Lu-Min Shih +5 more
doaj +1 more source
Contributions of Dickkopf‐1 to Obesity‐Induced Bone Loss and Marrow Adiposity
JBMR Plus, 2020 Low bone strength in overweight individuals is a significant medical problem. One important determinant of mesenchymal stem cell fate into osteoblasts or adipocytes is the Wnt signaling pathway.
Juliane Colditz +3 more
doaj +1 more source
Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men
Frontiers in Physiology, 2017 Introduction/Purpose: A number of studies have investigated the effect of training with a moderate exercise dose (3–6 h/weekly) on the inflammatory profile in blood, and the data are inconsistent.
Ronni E. Sahl +10 more
doaj +1 more source
Cell Death and Disease, 2022 Metabolic disorders and abnormal immune function changes occur in tumor tissues and cells to varying degrees. There is increasing evidence that reprogrammed energy metabolism contributes to the development of tumor suppressive immune microenvironment and
Lin Zhao +6 more
doaj +1 more source
Frontiers in Human Neuroscience, 2021 Substantial evidence indicates that cognitive training can be efficacious for older adults, but findings regarding training-related brain plasticity have been mixed and vary depending on the imaging modality.
Ania Mikos +5 more
doaj +1 more source
Drugs and Healthy Aging. [PDF]
Drugs AgingAbstract Appropriate drug treatment can enhance the likelihood of experiencing healthy aging and maintaining functional ability up to very late in life. Strong evidence exists that overall drugs can help prevent and manage diseases. However, such evidence is mostly available from studies that are not representative of older people and do not ...
Hilmer SN, Ferrucci L, Cherubini A.
europepmc +3 more sources
Cells, 2021 7-Ketocholesterol (7KCh) is a major oxidized cholesterol product abundant in lipoprotein deposits and atherosclerotic plaques. Our previous study has shown that 7KCh accumulates in erythrocytes of heart failure patients, and further investigation ...
Mei-Ling Cheng +6 more
doaj +1 more source
Foods, 2022 Histidine (His) carries a unique heteroaromatic imidazole side chain and plays an irreplaceable role in peptides and proteins. With the current study, we aimed to determine the characteristics and functional activities of the bone density of soy peptide ...
Jing Gan +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source