Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Weight loss and physical activity after total knee replacement: Study protocol for the Healthy Living randomized controlled trial. [PDF]
Pellegrini CA +12 more
europepmc +1 more source
Randomized-controlled trial of a whole-family obesity prevention and treatment intervention designed for low-income Hispanic families: HeLP the healthy living program. [PDF]
Haemer M +9 more
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Nutrition Practices for Healthy Living Across the Lifespan in Black/African American Men. [PDF]
Turner L, Castor C, Ntekim O.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Sarcopenia, healthy living, and mortality in patients with chronic liver diseases. [PDF]
Van Dongen C +7 more
europepmc +1 more source
Reflecting on a decade of action: a review of select indicators for the Israel National Program for Active and Healthy Living-Efsharibari, 2011-2022. [PDF]
Levi S +3 more
europepmc +1 more source
A united approach to promoting healthy living behaviours and associated health outcomes: a global call for policymakers and decisionmakers. [PDF]
Faghy MA +4 more
europepmc +1 more source

