Results 191 to 200 of about 609,352 (314)

Healthy living environments create healthy physical activity-related habits (ELEVATE): A protocol for a smartphone-based mixed-method study. [PDF]

PLoS One
Helbich M, Labib SM, Liedtke I, Sent D, Crombag R, Ettema D, Posthumus H, van der Zee S, Reiling M, Ruinaard S, van Mispelaar A, Brombacher A, Hoyng J, Spierings B, Savenije W.   +14 more
europepmc   +1 more source

Towards the new generation of courtyard buildings as a healthy living concept for post-pandemic era. [PDF]

Sustain Cities Soc, 2023
Saadatjoo P, Badamchizadeh P, Mahdavinejad M.   +2 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

The Where and the How:: Ensuring those with Disabilities have the People Power for Healthy Living. [PDF]

Dela J Public Health, 2022
Wright C, Hensley V, Emery N, Swanson P.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Multilevel obstacles to heart-healthy living in the context of Ischemic heart disease: A qualitative study. [PDF]

PLoS One
Amidi B, Naderi N, Yoosefi Lebni J, Amin A.   +3 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Weight loss and physical activity after total knee replacement: Study protocol for the Healthy Living randomized controlled trial. [PDF]

Osteoarthr Cartil Open
Pellegrini CA, Wilcox S, Kennerley C, Lee J, Turner-McGrievy G, Regan E, Wessinger P, Chen B, Davis HT, Jamieson S, Horn K, Stansbury M, Jackson JB.   +12 more
europepmc   +1 more source

Editorial: The impact of sedentary behavior and virtual lifestyle on physical and mental wellbeing: social distancing from healthy living. [PDF]

Front Public Health, 2023
Hanna F, You E, El-Sherif M.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source