Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The role of moderating variables in the relationship between health literacy and healthy living awareness among health program students: a cross-sectional study. [PDF]
BMC Public HealthGülşen M, Bozer Uludağ C, Binokay H.
europepmc +1 more source
Editorial: Exercise Prescription and Psychological Determinants for Healthy Living. [PDF]
Front Psychol, 2022 Bonato M +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
SEM-ANN analysis of the social prescription of nature, physical activity, and healthy living initiatives for cardiovascular health: mediating role of social support. [PDF]
Front Public HealthMenhas R.
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Role of Physical Activity Opportunities and Local Authority Engagement in Promoting Healthy Living and Increasing Life Expectancy. [PDF]
Healthcare (Basel)Mangra MG +5 more
europepmc +1 more source
Digital interventions in the management of advanced liver disease: Prescription and monitoring of healthy living in homes. [PDF]
Clin Liver Dis (Hoboken), 2022 Choi C, Simonetto DA.
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source