Results 21 to 30 of about 191,553 (318)

Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants

open access: yesComputational and Structural Biotechnology Journal, 2022
When hearing fails, electrical cochlear implants (eCIs) partially restore hearing by direct stimulation of spiral ganglion neurons (SGNs). As light can be better confined in space than electrical current, optical CIs (oCIs) provide more spectral ...
Lakshay Khurana   +3 more
doaj   +1 more source

Inner ear therapeutics and the war on hearing loss: systemic barriers to success

open access: yesFrontiers in Neuroscience, 2023
Despite over 20 years of effort in academic research centers, start-up companies, and established pharmaceutical companies, there are no FDA-approved inner ear therapeutics for treatment of sensorineural hearing loss.
Nicole T. Jiam, Steven D. Rauch
doaj   +1 more source

Cochlear implantation performance outcomes in patients over 80 years old

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Objective To examine device datalogging characteristics and postoperative performance in the very elderly CI users. Methods Retrospective chart review of postoperative speech recognition outcomes and datalogging characteristics in patients older than 80 ...
Helena Wichova   +4 more
doaj   +1 more source

Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants

open access: yesFrontiers in Molecular Neuroscience, 2021
Optogenetic stimulation of type I spiral ganglion neurons (SGNs) promises an alternative to the electrical stimulation by current cochlear implants (CIs) for improved hearing restoration by future optical CIs (oCIs).
Antoine Tarquin Huet   +13 more
doaj   +1 more source

Which Came First, Age-Related Hearing Loss with Tinnitus or Cognitive Impairment? What are the Potential Pathways?

open access: yesJournal of Integrative Neuroscience, 2023
Research on the causal relationship between age-related hearing loss (ARHL) and/or tinnitus and dementia is an important and fast-moving field. In this opinion paper, the up-to-date evidence and potential mechanisms for the bidirectional relationship are
Qingwei Ruan, Bing Chen, Francesco Panza
doaj   +1 more source

Conversations in Cochlear Implantation: The Inner Ear Therapy of Today

open access: yesBiomolecules, 2022
As biomolecular approaches for hearing restoration in profound sensorineural hearing loss evolve, they will be applied in conjunction with or instead of cochlear implants. An understanding of the current state-of-the-art of this technology, including its
Grant Rauterkus   +4 more
doaj   +1 more source

Neurofibromatosis 2: hearing restoration options. [PDF]

open access: yesBraz J Otorhinolaryngol, 2012
Neurofibromatosis 2 (NF2) is an autosomal dominant disease in which hearing loss is predominant. Auditory restoration is possible using cochlear implants (CI) or auditory brainstem implant (ABI).To assess the auditory results of CI and ABI in NF2 patients and review the literature.Four NF2 patients were prospectively evaluated.
Monteiro TA   +5 more
europepmc   +4 more sources

Understanding and treating paediatric hearing impairment

open access: yesEBioMedicine, 2021
Sensorineural hearing impairment is the most frequent form of hearing impairment affecting 1–2 in 1000 newborns and another 1 in 1000 adolescents. More than 50% of congenital hearing impairment is of genetic origin and some forms of monogenic deafness ...
Christian Wrobel   +2 more
doaj   +1 more source

Hearing Restoration in Neurofibromatosis Type II Patients. [PDF]

open access: yesYonsei Med J, 2016
Patients with neurofibromatosis type II will eventually succumb to bilateral deafness. For patients with hearing loss, modern medical science technology can provide efficient hearing restoration through a number of various methods. In this article, several hearing restoration methods for patients with neurofibromatosis type II are introduced.
Lee JM   +4 more
europepmc   +5 more sources

Preventing Hearing Loss and Restoring Hearing: A New Outlook [PDF]

open access: yesBioMed Research International, 2015
People with hearing loss represent one of the largest disability groups worldwide, and the prevalence of hearing loss is predicted to rise with an ageing population. Substantial progress has been made towards understanding some of the biological processes involved in the development of hearing impairment as well as therapeutic ways to prevent or ...
Vlajkovic, SM   +3 more
openaire   +4 more sources

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