Results 71 to 80 of about 412,112 (380)

Biomimetic electromechanical stimulation to maintain adult myocardial slices in vitro

open access: yesNature Communications, 2019
Cultured adult cardiac tissue undergoes rapid dedifferentiation, which hinders chronic in vitro studies. Here the authors investigate biomimetic electromechanical stimulation of adult myocardial slices applying different preload conditions, identifying ...
Samuel A. Watson   +11 more
doaj   +1 more source

Surgeon Speaks [PDF]

open access: yes, 2017
Like every surgeon, I started my residency training in General Surgery. Then I specialized in Thoracic and Cardiovascular Surgery and finally sub-specialized with a Fellowship in Heart and Lung Transplantation and Adult Cardiac Surgery at Duke University

core   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou   +10 more
wiley   +1 more source

Different behaviour of BK-virus infection in liver transplant recipients [PDF]

open access: yes, 2016
Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts ...
MITTERHOFER, Anna Paola   +3 more
core   +2 more sources

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

open access: yesAdvanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang   +25 more
wiley   +1 more source

2015 ESC/ERS GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION

open access: yesРоссийский кардиологический журнал, 2016
The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC ...
Nazzareno Galiè   +20 more
doaj   +1 more source

A High‐Throughput AngioPlate Platform with Integrated AngioTEER for Modeling and Monitoring Renal Proximal Tubule Injury

open access: yesAdvanced Materials Technologies, EarlyView.
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar   +13 more
wiley   +1 more source

An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA. [PDF]

open access: yes, 2015
Antibody-mediated rejection (AMR) of solid organ transplants (SOT) is characterized by damage triggered by donor-specific antibodies (DSA) binding donor Class I and II HLA (HLA-I and HLA-II) expressed on endothelial cells.
Fishbein, MC   +7 more
core   +1 more source

Anisotropic Surface Microrollers for Endovascular Navigation: A Computational Analysis with a Case Study in Hepatic Perfusion

open access: yesAdvanced Theory and Simulations, EarlyView.
Computational fluid dynamics analyses assess the upstream locomotion performance of anisotropic microrollers with varying height‐to‐width ratios. Observing their successful upstream locomotion in veins, their performance in hepatic circulation is investigated for treating primary liver cancer.
Burak Arslan   +8 more
wiley   +1 more source

Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells

open access: yesStem Cell Research & Therapy, 2017
Background Human dental mesenchymal stem cells (MSCs) are considered as highly accessible and attractive MSCs for use in regenerative medicine, yet some of their features are not as well characterized as other MSCs.
Victor G. Martinez   +8 more
doaj   +1 more source

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