Pathology of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon Salmo salar [PDF]
This is the first description of heart and skeletal muscle inflammation (HSMI), a novel disease affecting farmed Atlantic salmon Salmo salar in Norway. HSMI was first diagnosed in 1999, and there has since been a yearly increase in the number of recorded outbreaks.
R T, Kongtorp, T, Taksdal, A, Lyngøy
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Heart and skeletal muscle inflammation – novel dangerous disease of farmed Salmonidae
Heart and skeletal muscle inflammation (HSMI) is one of the most widespread economically relevant diseases of farmed Atlantic salmon (Salmo salar), and it poses serious danger to its aquaculture. The disease was first reported in Norway in 1999. In 2006, the Norwegian researchers demonstrated its viral etiology.
V. P. Melnikov, V. V. Pronin
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Risk mapping of heart and skeletal muscle inflammation in salmon farming
Heart and skeletal muscle inflammation (HSMI) is an infectious disease causing losses to the Norwegian salmon farming industry due to increased mortality and high morbidity in infected salmon. The disease is listed as a notifiable disease on list 3 (national list) by the Norwegian Food Safety Authority.
Kristoffersen, Anja B. +2 more
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Background: Peripheral myopathy consists a hallmark of heart failure (HF) and has been associated with poor prognosis. Inflammation has been suggested to dominate this pathology, while exercise training is typically associated with the induction of anti-inflammatory mechanisms.
Anastassios Philippou +5 more
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Immunohistochemical detection of piscine reovirus (PRV) in hearts of Atlantic salmon coincide with the course of heart and skeletal muscle inflammation (HSMI) [PDF]
Aquaculture is the fastest growing food production sector in the world. However, the increased production has been accompanied by the emergence of infectious diseases. Heart and skeletal muscle inflammation (HSMI) is one example of an emerging disease in farmed Atlantic salmon (Salmo salar L).
Finstad Øystein +4 more
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Atlantic salmon (Salmo salar L.) mariculture has been associated with epidemics of infectious diseases that threaten not only local production, but also wild fish coming into close proximity to marine pens and fish escaping from them. Heart and skeletal muscle inflammation (HSMI) is a frequently fatal disease of farmed Atlantic salmon. First recognized
Palacios, Gustavo F. +18 more
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Clinical frailty affects ∼10% of people over age 65 and is studied in a chronically inflamed (Interleukin-10 knockout; “IL10-KO”) mouse model. Frailty phenotypes overlap the spectrum of diseases (“laminopathies”) caused by mutations in LMNA. LMNA encodes nuclear intermediate filament proteins lamin A and lamin C (“lamin A/C”), important for tissue ...
Fatima D. Elzamzami +9 more
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Inactive trans-sialidase expression in iTS-null Trypanosoma cruzi generates virulent trypomastigotes [PDF]
Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence.
Bertelli, Adriano +6 more
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Novel treatment strategies for chronic kidney disease: insights from the animal kingdom [PDF]
Many of the >2 million animal species that inhabit Earth have developed survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular ageing; however, some animals remain susceptible to these ...
Arnold, Walter +7 more
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Hypothesis: ‘Vasocrine’ signalling from perivascular fat - a mechanism linking insulin resistance and vascular disease [PDF]
Adipose tissue expresses cytokines which inhibit insulin signalling pathways in liver and muscle. Obesity also results in impairment of endothelium-dependent vasodilatation to insulin. We propose a vasoregulatory role for local deposits of fat around the
Eringa, E. +2 more
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