Results 21 to 30 of about 82,439 (260)

The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition [PDF]

, 2010
Many disease states are associated with regional or systemic hypoxia. The study of healthy individuals exposed to high-altitude hypoxia offers a way to explore hypoxic adaptation without the confounding effects of disease and therapeutic interventions ...
Grocott Mike P., Edwards, Lindsay M, Holloway, CJ, Mike P Grocott, Grocott, Mike P, Edwards, LM, Neubauer, Stefan, Hugh E Montgomery, Murray Andrew J., Peter A Robbins, Robbins Peter A., Robbins, Peter A., Montgomery, Hugh E., Robbins, Peter A, Grocott, Mike P.W., Tyler Damian J., Earnest, Conrad P., Holloway Cameron J., Damian J Tyler, Murray, Andrew J, Caudwell Xtreme Everest Research Group, Clarke Kieran, Montgomery, Hugh E, Kemp Graham J., Andrew J Murray, Murray, AJ, ?, ?, Neubauer Stefan, Clarke, K, Robbins, Peter, Denny Levett, Holloway, Cameron J, Holloway, Cameron J., Kieran Clarke, Graham J Kemp, Montgomery Hugh E., Murray, Andrew J., Grocott, Mike P., Levett Denny, Grocott, MP, Caudwell Xtreme Everest Res Grp, Lindsay M Edwards, Tyler, Damian, Robbins, PA, Edwards, Lindsay M., Kemp, Graham J, Montgomery, HE, Tyler, Damian J, Levett, D, Kemp, Graham J., Neubauer, S, Tyler, DJ, Kemp, GJ, Levett, Denny, Clarke, Kieran, Cameron J Holloway, Tyler, Damian J., Stefan Neubauer, Edwards Lindsay M.   +58 more
core   +1 more source

The molecular dissection of the regulation of PGC-1α and the genome-wide activity of its transcriptional network in skeletal muscle cells [PDF]

, 2013
The transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a potent inducer of mitochondrial biogenesis and oxidative metabolism.
Barešić, Mario
core   +1 more source

External physical and biochemical stimulation to enhance skeletal muscle bioengineering [PDF]

, 2015
Cell based muscle tissue engineering carries the potential to revert the functional loss of muscle tissue caused by disease and trauma. Although muscle tissue can be bioengineered using various precursor cells, major limitations still remain.; In the ...
Handschin, Christoph, Eberli, Daniel, Mortezavi, Ashkan, Plock, Jan, Plock, Jan; https://orcid.org/, Eberli, Daniel; https://orcid.org/   +5 more
core   +1 more source

The role of the coactivators PGC-1α and PGC-1β in retina and skeletal muscle [PDF]

, 2011
Peroxisome proliferator-activated receptor γ coactivator- 1 (PGC-1) designates a family of coactivators consisting of PGC-1α, PGC-1β and PRC. By associating with transcription factors like nuclear receptors, they induce transcription of target genes that
Egger, A, Egger, Anna Franziska
core   +1 more source

Current Understanding of Molecular Pathology and Treatment of Cardiomyopathy in Duchenne Muscular Dystrophy

Molecules, 2015
Duchenne muscular dystrophy (DMD) is a genetic muscle disorder caused by mutations in the Dmd gene resulting in the loss of the protein dystrophin. Patients do not only experience skeletal muscle degeneration, but also develop severe cardiomyopathy by ...
Tirsa L. E. van Westering, Corinne A. Betts, Matthew J. A. Wood   +2 more
doaj   +1 more source

Exercise as a Therapeutic Strategy for Sarcopenia in Heart Failure: Insights into Underlying Mechanisms

Cells, 2020
Sarcopenia, a syndrome commonly seen in elderly populations, is often characterized by a gradual loss of skeletal muscle, leading to the decline of muscle strength and physical performance.
Jinkyung Cho, Youngju Choi, Pavol Sajgalik, Mi-Hyun No, Sang-Hyun Lee, Sujin Kim, Jun-Won Heo, Eun-Jeong Cho, Eunwook Chang, Ju-Hee Kang, Hyo-Bum Kwak, Dong-Ho Park   +11 more
doaj   +1 more source

Optimal management of sarcopenia [PDF]

, 2010
Sarcopenia is the progressive generalized loss of skeletal muscle mass, strength, and function which occurs as a consequence of aging. With a growing older population, there has been great interest in developing approaches to counteract the effects of ...
Sumukadas, Deepa, Louise A Burton, Burton, Louise A., Deepa Sumukadas   +3 more
core   +1 more source

Genetic grouping and geographic distribution of Piscine orthoreovirus-1 (PRV-1) in farmed Atlantic salmon in Norway

Veterinary Research, 2021
Piscine orthoreovirus-1 (PRV-1) is the causative agent of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). However, it has been shown that PRV-1 variants differ in their ability to induce HSMI.
Nina A. Vatne, Marit Stormoen, Morten Lund, Magnus Devold, Espen Rimstad, Øystein Wessel   +5 more
doaj   +1 more source

Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats

AIDS Research and Therapy, 2008
Background Human immunodeficiency virus type 1 (HIV-1) infection and the consequent acquired immunodeficiency syndrome (AIDS) has protean manifestations, including muscle wasting and cardiomyopathy, which contribute to its high morbidity.
Guidot David M, Brown Lou, Ashikhmin Yaroslav I, Otis Jeffrey S   +3 more
doaj   +1 more source

Study protocol to investigate the effects of testosterone therapy as an adjunct to exercise rehabilitation in hypogonadal males with chronic heart failure

, 2006
Testosterone deficiency is a common occurrence in men with chronic heart failure (CHF) and may underpin features of advanced disease, including reduced skeletal muscle mass and fatigue.
Mathur, Atish, Zwierska, Irena, Saxton, John, Saxton, John M, Channer, Kevin S, Channer, Kevin   +5 more
core   +1 more source