Results 21 to 30 of about 81,682 (247)

CD38‐NADase is a new major contributor to Duchenne muscular dystrophic phenotype

EMBO Molecular Medicine, 2022
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration. Two important deleterious features are a Ca2+ dysregulation linked to Ca2+ influxes associated with ryanodine receptor hyperactivation, and a muscular nicotinamide ...
Antoine de Zélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de la Porte   +24 more
doaj   +1 more source

Cardiac transplantation in dermatomyositis: A case report and literature review

Human Pathology: Case Reports, 2017
Background and objectives: Cardiac involvement has been well recognized in patients with dermatomyositis (DM) and polymyositis (PM) with a variable frequency between 9 and 72%.
Sangmee Bae, Negar Khanlou, Christina Charles-Schoeman   +2 more
doaj   +1 more source

Risk mapping of heart and skeletal muscle inflammation in salmon farming

Preventive Veterinary Medicine, 2013
Heart and skeletal muscle inflammation (HSMI) is an infectious disease causing losses to the Norwegian salmon farming industry due to increased mortality and high morbidity in infected salmon. The disease is listed as a notifiable disease on list 3 (national list) by the Norwegian Food Safety Authority.
Kristoffersen, Anja B., Bang Jensen, Britt, Jansen, Peder A.   +2 more
openaire   +2 more sources

Heart and Skeletal Muscle Inflammation of Farmed Salmon Is Associated with Infection with a Novel Reovirus

PLoS ONE, 2010
Atlantic salmon (Salmo salar L.) mariculture has been associated with epidemics of infectious diseases that threaten not only local production, but also wild fish coming into close proximity to marine pens and fish escaping from them. Heart and skeletal muscle inflammation (HSMI) is a frequently fatal disease of farmed Atlantic salmon. First recognized
Palacios, Gustavo F., Lovoll, Marie, Tengs, Torstein, Hornig, Mady, Hutchison, Stephen, Hui, Jeffrey, Kongtorp, Ruth-Torill, Savji, Nazir, Bussetti, Ana, Solovyov, Alexander V., Kristoffersen, Anja B., Celone, Christopher, Street, Craig, Trifonov, Vladimir, Hirschberg, David L., Rabadan, Raul, Egholm, Michael, Rimstad, Espen, Lipkin, W. Ian   +18 more
openaire   +5 more sources

Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation

Skeletal Muscle, 2019
Skeletal muscle myopathy and exercise intolerance are diagnostic hallmarks of heart failure (HF). However, the molecular adaptations of skeletal muscles during dilated cardiomyopathy (DCM)-mediated HF are not completely understood.Skeletal muscle structure and function were compared in wild-type (WT) and cardiac myosin binding protein-C null mice (t/t),
Taejeong Song, Palanikumar Manoharan, Douglas P. Millay, Sheryl E. Koch, Jack Rubinstein, Judith A. Heiny, Sakthivel Sadayappan   +6 more
openaire   +3 more sources

Current Understanding of Molecular Pathology and Treatment of Cardiomyopathy in Duchenne Muscular Dystrophy

Molecules, 2015
Duchenne muscular dystrophy (DMD) is a genetic muscle disorder caused by mutations in the Dmd gene resulting in the loss of the protein dystrophin. Patients do not only experience skeletal muscle degeneration, but also develop severe cardiomyopathy by ...
Tirsa L. E. van Westering, Corinne A. Betts, Matthew J. A. Wood   +2 more
doaj   +1 more source

Exercise as a Therapeutic Strategy for Sarcopenia in Heart Failure: Insights into Underlying Mechanisms

Cells, 2020
Sarcopenia, a syndrome commonly seen in elderly populations, is often characterized by a gradual loss of skeletal muscle, leading to the decline of muscle strength and physical performance.
Jinkyung Cho, Youngju Choi, Pavol Sajgalik, Mi-Hyun No, Sang-Hyun Lee, Sujin Kim, Jun-Won Heo, Eun-Jeong Cho, Eunwook Chang, Ju-Hee Kang, Hyo-Bum Kwak, Dong-Ho Park   +11 more
doaj   +1 more source

Skeletal muscle–heart crosstalk in chronic kidney disease: hierarchical signaling networks underlying myocardial metabolic reprogramming and fibrotic remodeling

Frontiers in Physiology
Cardiovascular disease is a major complication of chronic kidney disease (CKD) and often develops alongside skeletal muscle wasting and sarcopenia. These abnormalities are usually studied as separate consequences of CKD, but they may also be linked ...
Haijing Lu, Boyin Liu, Jiazhou Ji, Lin Shuai, Jingyuan Cao   +4 more
doaj   +1 more source

Genetic grouping and geographic distribution of Piscine orthoreovirus-1 (PRV-1) in farmed Atlantic salmon in Norway

Veterinary Research, 2021
Piscine orthoreovirus-1 (PRV-1) is the causative agent of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). However, it has been shown that PRV-1 variants differ in their ability to induce HSMI.
Nina A. Vatne, Marit Stormoen, Morten Lund, Magnus Devold, Espen Rimstad, Øystein Wessel   +5 more
doaj   +1 more source

Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats

AIDS Research and Therapy, 2008
Background Human immunodeficiency virus type 1 (HIV-1) infection and the consequent acquired immunodeficiency syndrome (AIDS) has protean manifestations, including muscle wasting and cardiomyopathy, which contribute to its high morbidity.
Guidot David M, Brown Lou, Ashikhmin Yaroslav I, Otis Jeffrey S   +3 more
doaj   +1 more source