BACKGROUND: There is a growing need to improve myocardial protection, which will lead to better performance of cardiac operations and reduce morbidity and mortality.
Melchior Luiz Lima +5 more
doaj +1 more source
Targeted Temperature Management at 36°C after In-Hospital Cardiac Arrest Trial (TTM-36 IHCA Trial): Study Protocol for an Investigator-Initiated, Single-Center, Randomized, Controlled, Assessor-Blinded, Pilot Clinical Trial [PDF]
Background: Targeted temperature management (TTM) has neuroprotective effects in comatose patients despite restoration of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest.
doaj +1 more source
Sudden cardiac arrest is a leading cause of death in the United States. The neurophysiological mechanism underlying sudden death is not well understood.
Fangyun Tian +18 more
doaj +1 more source
Identification of the growth arrest and DNA damage protein GADD34 in the normal human heart and demonstration of alterations in expression following myocardial ischaemia [PDF]
Growth arrest and DNA damage protein 34 (GADD34) is a multifunctional protein upregulated in response to cellular stress and is believed to mediate DNA repair and restore protein synthesis. In the present study we have examined GADD34 immunoreactivity in
Brown +15 more
core +1 more source
Cardiovascular Remodeling Experienced by Real-World, Unsupervised, Young Novice Marathon Runners. [PDF]
Aims: Marathon running is a popular ambition in modern societies inclusive of non-athletes. Previous studies have highlighted concerning transient myocardial dysfunction and biomarker release immediately after the race.
Aengevaeren +92 more
core +2 more sources
Alternative Splicing of Pericentrin Contributes to Cell Cycle Control in Cardiomyocytes
Induction of cardiomyocyte proliferation is a promising option to regenerate the heart. Thus, it is important to elucidate mechanisms that contribute to the cell cycle arrest of mammalian cardiomyocytes.
Jakob Steinfeldt +3 more
doaj +1 more source
Introduction: Few data can be found about cardiac arrest in the intensive care unit outside reference centers in third world countries. Objective: To study epidemiology and prognostic factors associated with cardiac arrest in the intensive care unit ...
Leonardo Augusto Miana +6 more
doaj +1 more source
Objectives: To compare 1-year all-cause mortality and major adverse cardiovascular events in cardiac arrest survivors with and without posttraumatic stress disorder symptomatology at hospital discharge. Design: Prospective, observational cohort. Setting:
S. Agarwal +8 more
semanticscholar +1 more source
Psoralen induced cell cycle arrest by modulating Wnt/β-catenin pathway in breast cancer cells
Psoralen could inhibit the proliferation of human breast cancer cells, however, the molecular mechanism was unclear. We evaluated the anti-proliferative effects of psoralen by MTT, plate colony formation assay and cell cycle analysis in MCF-7 and MDA-MB ...
Xiaohong Wang +10 more
semanticscholar +1 more source
Evaluation of the Appropriate Root Pressure for Maintaining Heartbeat during an Aortic Cross-clamp for Primary Repair of the Aortic Arch in Premature Infants with Associated Cardiac Anomalies [PDF]
We developed a new cardiopulmonary bypass (CPB) method to minimize myocardial damage during aortic arch reconstruction. In this method, coronary flow and heartbeat were stabilized by maintaining the aortic root pressure with an adjusted preload of the ...
Honjo, Osami +5 more
core +1 more source

